Phase I-II first-in-human clinical study of intraputamenal CDNF in Parkinson’s disease: Exploratory PET imaging endpoints of the 12-month treatment period
Objective: To test if intermittent intraputamenal monthly infusions of CDNF have an effect on striatal dopamine transporter (DAT) binding, as measured by PET, in subjects…CHIEF-PD: Cholinesterase Inhibitor to prEvent Falls in Parkinson’s Disease
Objective: Preventing falls in people with Parkinson’s disease has the potential to reduce hospital admissions and improve quality of life by diminishing the significant morbidity…Are effects of Rock Steady Boxing and PD SAFExTM on the motor symptoms of Parkinson’s disease maintained long-term? – A single-blinded randomized controlled trial
Objective: To determine if the benefits associated with RSB and PD SAFExTM on the motor symptoms of PD wash out over time. Background: Parkinson’s disease…Remote video-based research visits in a phase 3 clinical trial in Parkinson’s disease
Objective: To assess the feasibility, reliability, and value of remote visits in a phase 3 trial of individuals with Parkinson's disease (PD). Background: Remote video-based…Real-World Data on the Use of Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease who are Treated with Deep Brain Stimulation: The PD-DUAL Study
Objective: To examine the use of oral anti-parkinsonian medications in advanced Parkinson’s disease (APD) patients who have a history of, or current treatment with deep…Positive Correlations Between Quality of Life and Sleep Dysfunction in Advanced Parkinson’s Disease Patients Prior to and After 12 Months of Levodopa-Carbidopa Intestinal Gel Treatment: An Analysis From the DUOGLOBE Study
Objective: To evaluate the relationship between sleep disturbances and quality of life (QoL) in advanced Parkinson’s disease (PD) patients both prior to and at month…Epidemiology of Impulse Control Disorders and Association with Dopamine Agonist Exposure in the United States Military
Objective: Evaluate the epidemiology of impulse control disorders in the US Military and their association with dopamine agonist exposure. Background: Impulse control disorders (ICDs) are…An Analysis of Parkinson’s Disease Medication Treatment Patterns among Medicaid Patients
Objective: To describe patient demographic and medication utilization patterns within a state Medicaid program for patients diagnosed with Parkinson’s disease (PD). Background: Little is known…Opicapone management: A 2-year follow up real- life practice study
Objective: The aim of this work is to show our clinical experience with opicapone in real practice in a cohort of 68 parkinsonian patients followed…Effectiveness of onabotulinumtoxinA on reduction of rest tremor in Parkinson’s disease: A pilot study
Objective: To determine the feasibility of a prospective study design aimed specifically at comparing the effect of onabotulinumtoxinA (BOT-A) to placebo injections on persons with…
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