A phase 2b randomized, double-blind, placebo-controlled study of suvecaltamide in the treatment of adults with moderate to severe essential tremor: study design and methodology
Objective: Evaluate the efficacy and safety of JZP385 (formerly CX-8998), a highly selective T-type calcium channel modulator, for symptomatic control of moderate to severe essential…Both online and in-person JOBGRIP group training for people with Parkinson’s with paid employment is acceptable and perceived to be valuable
Objective: Explore acceptability and perceived efficacy of a group intervention for people with Parkinson’s diseases (PD) with paid employment. Background: PD leads to changes in…Autosomal recessive spinocerebellar ataxia type 10: a case report in Mexico
Objective: To provide a comprehensive description of the first clinical case of SCAR10 diagnosed in Mexico. Background: The autosomal recessive spinocerebellar ataxia type 10 is…NON-STRUCTURAL HEMICHOREA: REPORT OF NINE CASES
Objective: To analyze the etiology and clinical characteristics of patients with non-structural hemichorea treated in two neurology departments. Background: Hemichorea was classically associated with contralateral…Absence of neutralizing antibody formation during incobotulinumtoxinA treatment of spasticity in botulinum toxin-naïve children with cerebral palsy: pooled analysis of Phase 3 studies
Objective: To investigate neutralizing antibody (NAb) formation in three large Phase 3 studies with incobotulinumtoxinA, a botulinum neurotoxin type A (BoNT-A) with no complexing proteins,…Fatal Psychosis in a young Girl
Objective: We describe a 24-year young female who presented to us with features of Neurolept malignant syndrome. She was later evaluated and found to have…Current perspectives on the management of cervical dystonia among global clinicians
Objective: The aim of this study was to gain the perspectives of clinicians who treat patients with CD in terms of assessment and treatment goals,…Dystonia gravidarum: An emerging clinical entity
Objective: We describe a case of cervical dystonia in a 36 year-old, secundigravid, Caucasian woman at 8 weeks gestation. Background: Though uncommon, primary movement disorders…Diagnosis and management of Myoclonus Dystonia Syndrome: a Survey of the European Reference Network for Rare Neurological Diseases.
Objective: To evaluate the diagnostic and treatment strategies in Myoclonus Dystonia Syndrome (MDS) used by experts from the European Reference Network for rare neurological diseases…Neural Signals in the Cerebellar Nuclei Gate the Manifestation of Dystonia-Associated Symptoms in Mice
Objective: Define the differences in electrophysiological signatures of cerebellar output between mouse models of dystonia with diverse severity and manifestation. Background: Dystonia is heterogeneous movement…
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