BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.
Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…Altered functional connectivity of the hippocampus in posterior-cortical subtype of cognitive impairment in Parkinson’s disease
Objective: We aimed to delineate the dual syndrome subtypes of PD-MCI using a data-driven approach and explore hippocampal functional connectivity of the posterior-cortical syndrome. Background:…Progression of brain atrophy in Parkinson’s disease is shaped by connectome and local vulnerability
Objective: Using MRI data, the aim of this longitudinal study was to map the progression of brain atrophy over four years and relate it to…Normal-sized Perivascular Space in Basal Ganglia Related to Motor Phenotypes in Parkinson Freezers
Objective: With 7T MRI, we aimed to study the relationship between the initial motor phenotype of Parkinson’s disease (PD) and normal-sized PVSs (nPVSs) burden in…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Enhanced arm swing improves Parkinson gait associated with EEG power modulations resembling those in healthy gait.
Objective: To examine whether enhanced arm swing improves Parkinsonian gait and explore the role of the supplementary motor area (SMA) in such an improvement. Background:…Back pain in Parkinson’s disease: an underestimated problem
Objective: Estimate the importance of back pain (BP) in Parkinson's disease (PD) and its impact on quality of life. Background: Parkinson's disease (PD) is a…Nonmotor effects of subthalamic stimulation in Parkinson’s disease motor subtypes
Objective: To compare bilateral subthalamic stimulation (STN-DBS) effects on quality of life (QoL), motor, and nonmotor symptoms (NMS) in ‘tremor-dominant’ and ‘postural instability and gait…Maintenance of physical activity (PA) mitigates worsening of patient-reported outcomes in Parkinson’s disease (PD) during the COVID-19 pandemic
Objective: To examine changes in PD-patient reported outcomes during the COVID19 pandemic and the influence of changes in PA over the same period Background: Exercise interventions…Comparison of gastrointestinal transit times in typical and erratic levodopa-responders in patients with Parkinson’s disease.
Objective: To determine if altered transit time in the various segments of the gastrointestinal (GI) tract relates to the variability of clinical responses and serum…
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