GP2: training the next generation of Parkinson’s disease genetics researchers – wherever they are in the world
Objective: To establish a virtual ‘center of excellence’ with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org)…Monogenic Portal of the Global Parkinson’s Genetics Program (GP2)
Objective: To support the efforts of the Global Parkinson’s Genetics Program (GP2, http://gp2.org/) Monogenic Hub, by developing an easy-to-use online platform for case/family submission. Background:…Stratified genome-wide association study revealed novel interactions for the top hit Parkinson’s disease loci.
Objective: To identify genetic modifiers and interactors that may modulate known risk variants in the SNCA, TMEM175 and MAPT loci in Parkinson’s disease (PD). Background:…Antioxidants in foods: A Primary Potential remedy to Neurodegeneration.
Objective: The aim of the research is to establish the plausibility of reducing the effects of the actions of reactive oxygen species, produced by glutamate…The gut microbiome in Parkinson’s disease: longitudinal insights into disease progression and the use of device-assisted therapies.
Objective: We investigated the temporal stability of gut microbiome (GM) profiles from Parkinson’s disease (PD) patients initiating device-assisted therapies (DAT) and in a separate cohort…RNA Editing in Parkinson’s Disease Shows Changes in Mitochondrial and Manganese-Binding Pathways in Multiple Brain Regions
Objective: To identify RNA editing alterations associated with Parkinson’s disease (PD) in the Dorsal Motor Nucleus of the Vagus (DMV), Substantia Nigra (SN), and Cingulate…Deep learning based detection of Parkinson’s disease (PD) in Magnetic Resonance Imaging (MRI) brain scans
Objective: To use a deep learning based framework to classify MRI brain scans as PD or control cases. Background: The Parkinson’s Progression Markers Initiative provides…Usefulness of substantia nigra evaluation by transcranial ultrasonography in the diagnosis of Parkinson’s disease
Objective: To investigate the usefulness of transcranial ultrasonography (TCS) in the diagnosis of Japanese patients with Parkinson’s disease (PD). Background: There are many reports on…The association of β-amyloid with cognition and striatal dopamine in early, non-demented Parkinson’s disease
Objective: The purpose of this study was to investigate the association among striatal dopaminergic availability, Aβ-positivity, and motor and cognitive status in early and non-demented…Cognition-related functional topographies in Parkinson’s disease: Localized loss of the ventral default mode network
Objective: We sought to determine whether functional network abnormalities seen in patients with Parkinson’s disease (PD) and cognitive decline reflect the loss of the default…
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