Emotional processing and response times in Parkinson’s disease
Objective: The aim of this behavioural study was to test whether motor response is mainly driven by the emotional content of a picture or if…Analysis of effectiveness of Montreal Cognitive Assessment as cognitive evaluation method in low education level patients with Parkinson’s disease in the Brazilian Amazon.
Objective: To analyze the effectiveness of Montreal Cognitive Assessment (MoCA) to define dementia in low education level patients with PD in the Brazilian Amazon. Background:…White matter and cognition in Parkinson’s disease
Objective: Examine whether a recently developed MRI biomarker intended to assess cerebrovascular small vessel disease, peak width of skeletonized mean diffusivity (PSMD)[1], predicts cognitive decline…The application of Next Generation Sequencing in the Parkinson Disease.
Objective: This study aims to better investigating the pathogenetic of PD and improving the diagnostic approach in the molecular genetics, using the NGS. Background: Parkinson’s…Monogenic Hub of the Global Parkinson’s Genetics Program (GP2): The 500-genomes pilot project
Objective: To identify novel monogenic causes of Parkinson’s disease (PD). Background: The Global Parkinson’s Genetics Program (GP2, http://gp2.org/) is an international collaborative effort that aims…Serial DaT-SPECT imaging in asymptomatic carriers of LRRK2 G2019S mutation: 8-years follow-up
Objective: To characterize the 8-year progression of clinical and imaging biomarkers in a cohort of asymptomatic LRRK2 G2019S carriers and to assess its utility as predictors of…Analysis of the HLA locus in isolated REM sleep behavior disorder and Lewy body dementia
Objective: To examine genetic association of HLA alleles and amino acid for isolated REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD). We compare…Effects of fine particulate matter and cigarette smoking on MPTP-induced dopaminergic neuronal cell death: Implication for Parkinson’s disease
Objective: The objective of this study was to determine the potential neurotoxicity of fine particulate matter (FPM) and the neuroprotective properties of nicotine in the pathogenesis…Induction of Parkinsonian-like changes via targeted down-regulation of astrocytic glutamate transporter GLT-1 in the striatum
Objective: The aim was to explore the function and mechanism of astrocytic GLT-1 in PD-like changes. Background: Numerous researches suggest decreased expression of glutamate transporter-1…Cerebral white matter atrophy may be associated with the performance of activities of daily livings in patients with Parkinson’s disease
Objective: To assess whether global or regional brain structural abnormalities are associated performance of activities of daily livings (ADL) in patients with Parkinson's disease (PD).…
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