MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Cognitive Impairment in Parkinson’s disease Patients: a Descriptive Study

    R. Nindela, A. Kurniawan, Y. Harun, S. Marisdina, I. Irfannuddin (Palembang, Indonesia)

    Objective: This study aims to describe the cognitive profile in Parkinson's disease (PD) patients. Background: Cognitive impairment is a common non-motor symptom of PD. Cohort…
  • MDS Virtual Congress 2021

    Effects of dopaminergic medication on reinforcement learning in Parkinson’s disease depend on depressive symptoms

    J. Tichelaar, C. Sayali, R. Helmich, R. Cools (Nijmegen, Netherlands)

    Objective: To investigate the effect of depression and dopaminergic medication on reinforcement learning (RL) in Parkinson’s disease. Background: Dopaminergic medication in PD is known to…
  • MDS Virtual Congress 2021

    A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson’s disease

    C. Fevga, Y. Park, E. Lohmann, A J. Kievit, G J. Breedveld, F. Ferraro, L. de Boer, R. van Minkelen, H. Hanagasi, A. Boon, W. Wang, G A. Petsko, Q Q. Hoang, M. Emre, V. Bonifati (Rotterdam, Netherlands)

    Objective: To report the identification of a novel variant in the gene encoding alpha-synuclein (SNCA), segregating with Parkinson’s Disease (PD) in two families of Turkish…
  • MDS Virtual Congress 2021

    Increased stroke risk in Parkinson’s disease patients with LRRK2 mutations

    D. Macias-Garcia, MT. Periñán, L. Muñoz-Delgado, S. Jesús, MV. Jimenez-Jaraba, D. Buiza-Rueda, M. Bonilla-Toribio, A. Adarmes-Gomez, F. Carrillo, P. Gómez-Garré, P. Mir (Seville, Spain)

    Objective: To determine whether genetic forms of Parkinson’s Disease (PD), such as LRRK2-mutated PD (LRRK2-PD) and GBA­-mutated PD (GBA­-PD), have a different vascular risk compared…
  • MDS Virtual Congress 2021

    Gut dysbiosis in Parkinson’s disease with motor complications

    K. Takahashi, H. Nishiwaki, M. Ito, K. Iwaoka, K. Yamahara, K. Takahashi, Y. Suzuki, K. Taguchi, Y. Tsuboi, K. Kashihara, M. Hirayama, K. Ohno, T. Maeda (Shiwa, Japan)

    Objective: We aimed to identify gut dysbiosis in Parkinson's disease patients with motor complications. Background: Recently, several evidences suggest that the gut microbiota is associated…
  • MDS Virtual Congress 2021

    Targeted plasmaproteome identifies a distinct biomarker panel in early and prodromal Parkinson’s disease

    M. Bartl, J. Hallqvist, M. Dakna, S. Schade, C. Trenkwalder, F. Sixel-Döring, B. Mollenhauer, K. Mills (Göttingen, Germany)

    Objective: To identify protein biomarkers in plasma of patients with Parkinson’s disease (PD). Background: Inflammation plays a key role in the initiation and progression of…
  • MDS Virtual Congress 2021

    Lipid metabolism alterations in the lysosomal membrane promotes chaperone-mediated autophagy dysfunction and alpha-synuclein pathology in Parkinson’s disease associated to GBA

    A. Navarro-Romero, I. Fernandez-Gonzalez, M. Montpeyo, J. Riera, E. Pradas, JA. Arranz, C. Carnicer-Caceres, M. Martinez-Vicente (Barcelona, Spain)

    Objective: The objective of this study was to generate and characterize a new in vitro neuronal model of Parkinson's diseases associated to GBA (PD-GBA) that…
  • MDS Virtual Congress 2021

    Substantia nigra pars compacta integrity is associated with DRT-related motor symptom improvement in Parkinson’s disease

    S. Atkinson, R. Seo, D. Peterson, B. Cholerton, SC. Hu, T. Montine, T. Grabowski, C. Zabetian, S. Rane (Seattle, USA)

    Objective: To study the correlation between substantia nigra white matter integrity and response of motor symptoms to dopamine replacement therapy (DRT) in Parkinson’s disease (PD).…
  • MDS Virtual Congress 2021

    Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA non-manifesting carriers

    A. Droby, M. Artzi, H. Lerman, RM. Hutchison, D. Ben Bashat, N. Omer, T. Gurevich, A. Orr-Urtreger, B. Cohen, J. Cedarbaum, E. Even Sapir, N. Giladi, A. Mirelman, A. Thaler (Tel Aviv, Israel)

    Objective: We aimed to study the association between presynaptic striatal dopamine uptake and functional connectivity (FC) patterns among healthy first-degree relatives of PD patients with…
  • MDS Virtual Congress 2021

    Patterns of Cortical Thinning in Patients with Parkinson’s Disease

    H. Jergas, JC. Baldermann, JN. Petry-Schmelzer, H. Dafsari, V. Visser-Vanderwalle, T. Dembek, M. Barbe (Cologne, Germany)

    Objective: To investigate patterns of cortical thickness that are associated with disease severity and response to levodopa. Background: Cortex affection is a neuropathological correlate of…
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