MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Neurofilament light chain serum levels in E46K-SNCA mutation carriers

    A. Murueta-Goyena, MA. Acera, N. Ayo, M. Carmona-Abellán, R. Del Pino, I. Gabilondo, B. Tijero, T. Fernandez, M. Ruiz, JC. Gómez-Esteban, E. Capetillo, R. Cipriani, F. Zallo, F. Cavaliere (Barakaldo, Spain)

    Objective: To demonstrate the usefulness of measuring the concentration of neurofilament light chain (NfL) in blood using Single Molecule Array matrix (SiMoA, Quanterix) as a…
  • MDS Virtual Congress 2021

    Association between Hippocampal Subfields, CSF Biomarkers, and Cognition in non-demented Parkinson’s patients

    S. Becker, O. Granert, M. Timmers, A. Pilotto, L. van Nueten, B. Roeben, G. Salvadore, W. Galpern, J. Streffer, K. Scheffler, W. Maetzler, D. Berg, I. Liepelt-Scarfone (Calgary, Canada)

    Objective: To determine whether hippocampal subfield volumes in non-demented Parkinson’s Disease (PD) are primarily predicted by cognition or CSF β-amyloid 1–42 (Aβ42) levels. Background: The…
  • MDS Virtual Congress 2021

    DAT-IQ improves power to detect longitudinal change in DaT deficit in SURE-PD3

    Z. Fan, J. Seibyl, K. Marek, M. Schwarzschild, E. Macklin, R. Gunn (London, United Kingdom)

    Objective: DATIQ has been developed as a novel analytical approach to improve the sensitivity and statistical efficiency of dopamine transporter (DaT) SPECT quantification over previously…
  • MDS Virtual Congress 2021

    BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.

    C. Koros, A-M. Simitsi, N. Papagiannakis, A. Prentakis, A. Bougea, D. Papadimitriou, R. Antonelou, I. Pachi, E. Angelopoulou, E. Stanitsa, I. Beratis, S. Papageorgiou, M. Stamelou, X. Trapali, L. Stefanis (Athens, Greece)

    Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…
  • MDS Virtual Congress 2021

    Altered functional connectivity of the hippocampus in posterior-cortical subtype of cognitive impairment in Parkinson’s disease

    D. Pourzinal, J. Yang, G. Byrne, J. O'Sullivan, L. Mitchell, K. Mcmahon, D. Copland, N. Dissanayaka (Herston, Australia)

    Objective: We aimed to delineate the dual syndrome subtypes of PD-MCI using a data-driven approach and explore hippocampal functional connectivity of the posterior-cortical syndrome. Background:…
  • MDS Virtual Congress 2021

    Progression of brain atrophy in Parkinson’s disease is shaped by connectome and local vulnerability

    C. Tremblay, S. Rahayel, A. Vo, F. Morys, G. Shafiei, R. Markello, Z. Gan-Or, B. Misic, A. Dagher (Montreal, Canada)

    Objective: Using MRI data, the aim of this longitudinal study was to map the progression of brain atrophy over four years and relate it to…
  • MDS Virtual Congress 2021

    Normal-sized Perivascular Space in Basal Ganglia Related to Motor Phenotypes in Parkinson Freezers

    Y. Yue, W. Lv, T. Shen, XY. Hu, H. Lai, F. Ba (Hangzhou, China)

    Objective: With 7T MRI, we aimed to study the relationship between the initial motor phenotype of Parkinson’s disease (PD) and normal-sized PVSs (nPVSs) burden in…
  • MDS Virtual Congress 2021

    Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease

    K. Cross, E. Koenig, J. Choi, N. Pouratian (Los Angeles, USA)

    Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…
  • MDS Virtual Congress 2021

    Enhanced arm swing improves Parkinson gait associated with EEG power modulations resembling those in healthy gait.

    J. Weersink, N. Maurits, B. de Jong (Groningen, Netherlands)

    Objective: To examine whether enhanced arm swing improves Parkinsonian gait and explore the role of the supplementary motor area (SMA) in such an improvement. Background:…
  • MDS Virtual Congress 2021

    Back pain in Parkinson’s disease: an underestimated problem

    B. Douma, I. Bedoui, M. Elfekih, H. Derbali, A. Riahi, M. Messelmani, M. Mansour, J. Zaouali, R. Mrissa (Sousse, Tunisia)

    Objective: Estimate the importance of back pain (BP) in Parkinson's disease (PD) and its impact on quality of life. Background: Parkinson's disease (PD) is a…
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