MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    LY-487,379 alleviates parkinsonism when administered as monotherapy in the MPTP-lesioned marmoset

    I. Frouni, C. Kwan, S. Nuara, S. Belliveau, A. Hamadjida, W. Kang, D. Bédard, J. Gourdon, P. Huot (Montreal, Canada)

    Objective: To determine the effect of selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulation as monotherapy on parkinsonism, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset. Background: We…
  • MDS Virtual Congress 2021

    LY-487,379 enhances the anti-parkinsonian action of a low dose of L-DOPA in the MPTP-lesioned marmoset

    C. Kwan, I. Frouni, S. Nuara, S. Belliveau, A. Hamadjida, W. Kang, D. Bédard, J. Gourdon, P. Huot (Montreal, Canada)

    Objective: To investigate the effect of selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulation on the anti-parkinsonian action of a low dose of…
  • MDS Virtual Congress 2021

    Effect of simultaneous mGlu2 positive allosteric modulation and orthosteric stimulation combined with 5-HT2A antagonism on psychosis-like behaviours, dyskinesia and parkinsonism in the MPTP-lesioned marmoset

    S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

    Objective: To assess the effects of concurrent metabotropic glutamate type 2 (mGlu2) positive allosteric modulation and orthosteric stimulation combined with serotonin type 2A (5-HT2A) antagonism.…
  • MDS Virtual Congress 2021

    Problems faced by Parkinson’s disease patients during COVID-19 pandemic compulsory lockdown and its management with the help of Telemedicine in a North Indian cohort

    K. Shukla, N. Sawal (Chandigarh, India)

    Objective: To study problems faced by PD patients during lockdown due lack of healthcare and medication procurement and address such problems using telemedicine via virtual…
  • MDS Virtual Congress 2021

    Safinamide Improves Pain in Parkinson´s Disease. Results from the SAFINONMOTOR Study.

    R. Yáñez, C. Labandeira, M. Cimas Hernando, I. Cabo, J. Paz González, M. Alonso Losada, M. González Palmás, C. Martínez, D. Santos García (Ourense, Spain)

    Objective: Our aim was to analyze the effectiveness of safinamide on pain in Parkinson´s disease (PD) patients from the SAFINONMOTOR (an open-label study of the…
  • MDS Virtual Congress 2021

    The effect of sleep positions on morning orthostatic hypotension in Multiple System Atrophy patients: A pilot study

    T. Prasertpan, J. Sringean, R. Bhidayasiri (Bangkok, Thailand)

    Objective: To determine the effect of sleep position on morning OH in MSA patients Background: Dysautonomia is considered as one of the most distress symptom…
  • MDS Virtual Congress 2021

    Automated Midbrain-Pons Ratio using Artificial Intelligence Differentiates PSP from other Atypical Parkinsonian Disorders

    M. Peres, G. Leroy, A. Gerhard, M. Hu, J. Klein, P. Leigh, A. Church, D. Burn, H. Morris, J. Rowe, T. Rittman (Cambridge, United Kingdom)

    Objective: Our primary goal was to implement an automated measure of the midbrain to pons ratio (MPR) using an artificial intelligence method. Our second objective…
  • MDS Virtual Congress 2021

    MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis

    R. Franco, TC. Aguiar, A. Morganho, P. Lobo, R. Dias, S. Aguiar (Funchal, Portugal)

    Objective: Case report presentation. Background: In frontotemporal dementia with parkinsonism (FTDP), several mutations in MAPT gene have been identified, and numerous family cases were reported,…
  • MDS Virtual Congress 2021

    Parkinsonism in a patient with limbic-predominant age-related TDP-43 encephalopathy (LATE) syndrome

    C. Selvadurai, S. Schaefer (New Haven, USA)

    Objective: To illustrate a case of parkinsonism in a patient with LATE syndrome. Background: LATE syndrome is an emerging subclassification of TDP-43 proteinopathy. Symptoms include…
  • MDS Virtual Congress 2021

    Physical activity and subjective perception of PD symptoms during COVID-19 lockdown: a clinical audit

    V. Foster, J. Pasquini, N. Pavese (Newcastle Upon Tyne, United Kingdom)

    Objective: To establish the effects of COVID-19 “lockdown” on physical activity and patients' perception of PD symptoms. Background: Physical activity in Parkinson Disease (PD) is…
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