Homozygous PRKN exon 3 deletion in an early-onset Parkinson’s disease family from the Kadazan-Dusun ethnic group indigenous to Sabah, Malaysia
Objective: To determine the causal gene for early-onset Parkinson’s disease (PD) in a Malaysian family of Kadazan-Dusun ethnicity. Background: Among Asian populations, relatively little is…Parkinson’s disease-linked LDL Receptor Related Protein 10 (LRP10) is implicated in regulation of the secretory and autophagy-lysosome pathways
Objective: We aim to investigate the potential roles of LRP10 defects in PD, PDD and DLB, focusing on two pathways known to be central in…Biofluid Biomarkers in Prodromal Parkinson’s Disease
Objective: To analyze biomarker signatures in biofluids in prodromal Parkinson’s disease (PD) to identify subjects at-risk to conversion and for progression. Background: Individuals at-risk for…Neurogenetic Traits Outline Vulnerability to Cortical Disruption in Parkinson’s Disease
Objective: In this study, we characterized the brain topological intersection between propagating connectivity networks in healthy controls (HC) and Parkinson’s disease (PD) participants and gene…A DIFFERENT RADIOLOGICAL PERSPECTIVE ON PARKINSON’S DISEASE AND PARKINSONISM: TRANSCRANIAL SONOGRAPHY
Objective: This study aims to investigate the reliability of Transcranial Sonography (TCS) in the diagnosis of Parkinson’s Disease (PD) and its contribution to the differential…Intrasubject subcortical quantitative referencing to make quantitative MRI sensitive to Parkinson’s disease
Objective: To assess the changes in R2* occurring in PD patients compared to controls, a multicenter transversal study was carried out in a large cohort of…Longitudinal structural and functional brain alterations in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical/subcortical grey matter (GM) changes and network functional alterations in PD-FoG patients, in PD developing FoG (PD-FoG-converters) and PD not developing…Motor symptom lateralization influences cortico-striatal functional connectivity in Parkinson’s disease
Objective: To evaluate the effect of lateralization on various cortico-striatal circuits through resting state functional MRI. Background: Striatum is unevenly impaired bilaterally in Parkinson’s disease.…Comorbid Moyamoya Disease and Parkinson’s disease: A case series
Objective: We report the first case series of comorbid Moyamoya disease (MMD) and Parkinson’s disease (PD). Background: MMD is characterized by angiographic findings of bilateral…Patient classification for adaptive deep brain stimulation
Objective: To explore a control theory modeling framework to classify which Parkinson’s disease patients may benefit from adaptive deep brain stimulation. Background: Deep brain stimulation…
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