Longitudinal clinical and biomarkers characteristics of non-manifest LRRK2 G2019S carriers: The PPMI cohort
Objective: To examine 2-year longitudinal change in clinical, dopamine transporter (DAT) imaging and biofluid biomarkers in non-manifesting carriers (NMCs) of LRRK2 G2019S versus healthy controls…Longitudinal study of Parkinson’s disease-related pattern with resting state functional MRI
Objective: To validate the previously characterized resting-state fMRI (rs-fMRI) Parkinson’s disease (PD)-related pattern, termed fPDRP, in a large multi-site PD imaging database, and to assess…P2B001 in the management of untreated PD. Results from a randomized, double-blind, double-dummy controlled trial
Objective: Evaluate the efficacy and safety of P2B001 compared with its components and with Extended-Release pramipexole (ER-PPX, calibration arm) in untreated PD. Background: P2B001 is…Postural Instability in Parkinson’s Disease: Phenotypic data from The Cincinnati Cohort Biomarker Program
Objective: To estimate the onset of postural instability in a cohort of Parkinson's disease (PD) patients. Background: The Cincinnati Cohort Biomarker Program (CCBP), launched in…Caregiving patients with Parkinson disease treated with deep brain stimulation: a systematic review and meta-synthesis of qualitative research
Objective: To explore the experiences and unmet needs of Parkinson disease patients (PDPs) caregivers after subthalamic nucleus deep brain stimulation (STN-DBS) by performing a systematic…Nutritional Status of Patients with Parkinson’s Disease: Report from Indonesian Tertiary Referral Hospital
Objective: This study aimed to describe and determine the prevalence of nutritional status in outpatient Parkinson’s Disease (PD) patients. Background: Parkinson’s disease is the most…Non-Invasive Brain Stimulation for the Treatment of Psychiatric Symptoms in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: This meta-analysis aims to assess the effect of NIBS technique for psychiatric symptoms in patients with PD. Background: Non-invasive brain stimulations (NIBS), especially repetitive…Imaging progressive peripheral and central dysfunction in isolated REM sleep behaviour disorder after 3 years of follow-up
Objective: To image progression of intestinal dysfunction, cardiac sympathetic denervation, and dopaminergic nigrostriatal damage in patients with isolated REM sleep behaviour disorder (iRBD). Background: A…[18F]FDG PET in hyperkinetic movement disorders: a systematic review
Objective: To give a comprehensive literature overview of alterations in regional cerebral glucose metabolism, measured using [18F]FDG PET, in hyperkinetic movement disorders. In addition, correlations…Muscarinic M2 cholinergic receptors in cervical dystonia
Objective: To characterize the M2 muscarinic acetylcholine receptor binding in patients with cervical dystonia, measured with non-invasive high-resolution PET, using [18F]FP-TZTP ligand. Background: While antimuscarinic…
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