A precompetitive consortium approach to designing a qualitative study to generate content validity evidence to support the use of digital health technologies among people with early Parkinson’s disease
Objective: To understand from the patient perspective the relevance and comprehensiveness of the performance outcome (PerfO) measures administered via digital health technologies (DHTs) in the…Motor, epileptic, and developmental phenotypes in genetic disorders affecting G-protein coupled receptor signaling and cAMP metabolism
Objective: To provide a detailed clinical characterization of genetic disorders affecting G-protein coupled receptor signaling and cAMP metabolism Background: Genetic disorders affecting G-protein coupled receptor (GPCRs) signaling…Safety and Efficacy of Verdiperstat, a Novel Myeloperoxidase Inhibitor, in MSA
Objective: To present results from M-STAR, a phase 3, randomized controlled trial evaluating the disease modifying effect of verdiperstat in participants with MSA. Background: MSA…Temporal Dynamic Alterations of Regional Homogeneity in Parkinson’s disease: A Resting-State fMRI Study
Objective: We aimed to test the differences of dynamic regional homogeneity (dReHo) between PD patients and healthy controls (HCs), and explore whether dReHo can be…A low-cost system using a big-data deep-learning framework for assessing physical tele-rehabilitation: a proof-of-concept
Objective: The consolidation of tele-rehabilitation for the treatment of many diseases over the last decades is a result of its cost-effective results and its ability…Paraneoplastic Cerebellar Ataxia Due To Ovarian Teratoma: A Case Report
Objective: report the case of a young woman who presented with rapidly progressive ataxia caused by an ovarian teratoma Background: paraneoplastic cerebellar degeneration (PCD) is…Influence of dopaminergig medication and subthalamic nucleus deep brain stimulation on impulsive decision making in Parkinson’s disease
Objective: To investigate how impulsive decision making is modulated by regular dopaminergic medication and by switching between active contacts of subthalamic nucleus stimulation Background: Impulsive…Color vision deficits in Parkinson’s disease are linked to brain abnormalities in attentional, fronto-pariental and visual networks
Objective: To analyze the relationship between color vision deficits in Parkinson’s disease (PD) and the integrity of the visual system, cognition and other relevant networks…Characteristics and Techniques to Improve Micrographia in Parkinson’s Disease
Objective: To analyze and identify the characteristics found in micrographia and provide methods of improving the symptom. Background: Micrographia, also known as small handwriting, is…More than medications: Patient and care partner perspectives on care for Parkinson’s during hospitalization
Objective: To document and assess the needs, experiences, and self-reported challenges among patients and care partners that impact optimal care for Parkinson's disease (PD) during hospitalization.…
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