MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2022 International Congress

    Clove mediated Rescue in Parkinson’s Disease involves modulation of p53 and Sestrin2 in SHSY5Y cell line model

    N. Rai, S. Dey (Udaipur, India)

    Objective: The study analyzed the neuroprotective effect of ethanolic extract of clove against Parkinson’s disease (PD) type toxicity in SHSY5Y cell line model and interrogation…
  • 2022 International Congress

    Caregiver burden in Parkinson’s Disease patients with Cardiovascular Dysautonomia

    C. Ledda, G. Imbalzano, C. Artusi, A. Merola, E. Montanaro, M. Zibetti, M. Rizzone, G. Sobrero, F. Vallelonga, S. Maule, L. Lopiano, A. Romagnolo (Turin, Italy)

    Objective: We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular…
  • 2022 International Congress

    A Potential Cluster Near Site of Dry Cleaning Contamination

    M. Pawlik, S. Lettenberger, M. Zafar, M. Coffey, A. Sarkar, P. Auinger, C. Tanner, S. Goldman, B. de Miranda, K. Kieburtz, R. Barbano, M. Braun, H. Schwarz, D. Kinel, R. Dorsey (Rochester, USA)

    Objective: To characterize specific health outcomes of people with potential exposure to chemicals used in dry cleaning. Background: Trichloroethylene (TCE) is a chlorinated solvent used…
  • 2022 International Congress

    Tissue Frataxin Increases After Administration of CTI-1601, a Frataxin Replacement Therapy in Development for the Treatment of Friedreich’s Ataxia

    D. Bettoun, T. Galas, D. Schecter, N. Ruiz, R. Clayton, J. Farmer (Bala Cynwyd, USA)

    Objective: To evaluate the pharmacodynamic (PD) and safety profiles of subcutaneous (SC) administration of multiple ascending doses of CTI-1601 in patients age ≥18 years with…
  • 2022 International Congress

    Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease

    A. Kopytova, M. Nikolaev, G. Baydakova, A. Izymchenko, D. Bogdanova, I. Miliukhina, A. Emelyanov, E. Zakharova, S. Pchelina (Gatchina, Russian Federation)

    Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…
  • 2022 International Congress

    Autonomic dysfunction and its correlation witn synucleinopathy: an immunohistological study in Tunisian patients with parkinson disease

    N. Ben Ali, L. Ali, S. Fezai, H. Jamoussi, S. Fray, M. Ben Mahmoud, M. Fredj (Tunis, Tunisia)

    Objective: Identify autonomic digestive symptoms of Parkinson disease (PD)Identify correlations between autonomic dysfunction and alpha-synuclein immunochemical staining in the upper digestive tract. Background: Pathological processes…
  • 2022 International Congress

    NPC1 is not a PD risk factor gene

    G. Barrel, M. Olmedillas, K. Kandaswamy, A. Westenberger, G. Hartmann, C. Klein, P. Bauer, C. Beetz (Rostock, Germany)

    Objective: To test the hypothesis of NPC1 to be a PD risk factor gene. Background: The many etiologies of PD include genetic risk factors. The…
  • 2022 International Congress

    Objective and easily performed assessment of fine motor skills to support the differential diagnosis of Parkinson’s disease and other movement disorders with tremor

    C. Papasavvas, R. Zietsma, S. Dodds, L. Cluitmans, A. Deutschlander, R. Walker (Edinburgh, United Kingdom)

    Objective: To assess the ability of a handheld device and its accompanying data analytics to distinguish between Parkinson’s disease (PD) and other tremor disorders. Background:…
  • 2022 International Congress

    Verifying imaging accuracy for targeting and lead positioning in DBS: a phantom study.

    A. Rohaan, Y. Willems, N. Vander Gaag (Leiden, Netherlands)

    Objective: In this phantom study we created an overview of the accuracy of four different modalities frequently used in DBS surgery and investigated the influence…
  • 2022 International Congress

    Sensorimotor retraining program based on the principles of S.P.R.Int (SensoriMotor perceptive Integrated) in association with E.M.D.R (Eye Movement Desensitization and Reprocessing): a new proposal for treatment in Functional Movement Disorders (FMD)- a case report

    A. Castagna, A. D'Amico, M. Genevini, M. Ramella (Milano, Italy)

    Objective: To propose a new multidisciplinary rehabilitation program based on association of sensorimotor retraining  and EMDR to treat FMD. Background: There is an emerging new…
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