Data-driven identification of distinct fronto-subcortical and cortical-posterior subtypes of cognitive decline in Parkinson’s disease
Objective: To use a novel data-driven approach, Subtype and Stage inference (SuStain)[1], for identifying distinct subtypes of domain-specific cognitive decline in Parkinson’s disease (PD), and…Speech disorders and axial motor impairment in advanced Parkinson’s Disease: two sides of the same coin?
Objective: To examine possible correlations between axial motor features, disease severity and speech parameters in advanced Parkinson’s Disease (PD) patients and to evaluate chronic dopaminergic…Feasibility of using mobile technology for aerobic exercise management in people with Parkinson’s disease
Objective: To examine the usability of a smartwatch heart rate monitor for monitoring aerobic exercise compliance during a 6-month brisk walking program, and to evaluate…Genetic correlation and potential causal relationship between inflammatory bowel disease and Parkinson’s disease
Objective: The present study investigates shared genetic etiology between inflammatory bowel disease (IBD) and Parkinson’s disease (PD) using correlation and causality-based approaches. Background: The role…Multiple N-of-1 trials to investigate hypoxia therapy in Parkinson’s disease: TALISMAN study rationale and protocol
Objective: This is the first study that will assess the potential impact of hypoxia-based therapy in individuals with PD on respiratory parameters and PD symptoms.…OPICAPONE ADD-ON THERAPY IN LEVODOPA-CARBIDOPA INTESTINAL GEL INFUSION: which patient might benefit the most?
Objective: To explore the benefit of Opicapone (OPC) add-on to levodopa-carbidopa intestinal gel (LCIG) in different phenotypes of Parkinson’s Disease (PD) patients. Background: LCIG monotherapy…Treatment of upper limb dystonic tremors: a retrospective study
Objective: Our study aimed to evaluate the clinical outcome of patients with upper-limb dystonic tremor (UL-DTs) treated at a tertiary hospital in London. Background: Tremor…Sporadic progressive ataxia and palatal tremor: a case series
Objective: To further characterize the clinical syndrome of sporadic progressive ataxia and palatal tremor (PAPT). Background: Defined by adult-onset progressive cerebellar features and tremor of…Impact of rs6265 in the Host and Donor on Dopamine Neuron Graft Function.
Objective: Extend investigations into the effect of the rs6265 single nucleotide polymorphism (SNP) on dopamine (DA) neuron graft efficacy using a parkinsonian rat model. Background:…Inducing motor cortical plasticity in Parkinson’s Disease patients using subthalamic deep brain stimulation and repetitive transcranial magnetic stimulation
Objective: To investigate whether motor cortical plasticity can be induced in Parkinson’s disease (PD) patients by pairing subthalamic deep brain stimulation (STN-DBS) and repetitive transcranial…
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