Quantity detection of Substantia nigra hyperechogenicity based on digital image analysis for diagnosing Parkinson’s disease
Objective: We aimed to apply digital analysis to quantify hyperechogenicity of Substantia nigra, and explore its clinical value for the diagnosis of PD. Background: Increased…Multimodal MRI assessment of the substantia nigra in premotor and motor stages of parkinsonism
Objective: To investigate substantia nigra (SN) MRI abnormalities through Neuromelanin (NM) and diffusion MRI (dMRI) with Neurite Orientation Dispersion and Density Index (NODDI) in the…Cross-cultural validation of the Cebuano version of a screening questionnaire for Parkinson’s Disease
Objective: To determine the validity of the Cebuano version of a PD screening questionnaire Background: In the Philippines, actual prevalence of Parkinson’s Disease (PD) is…Selection of clinical doses for SBT101, an AAV9-hABCD1 vector for the treatment of adrenomyeloneuropathy
Objective: To inform selection of doses of SBT101 for a first-in-human clinical study. SBT101 is an adeno-associated virus serotype 9 (AAV9)-based gene therapy candidate intended…Functional validation of a mitochondria-specific polygenic risk score in patient-based models for stratification of idiopathic Parkinson’s disease
Objective: The overall objective of this project is to gain essential knowledge on the contribution of genetic variability in nuclear-encoded mitochondrial proteins to idiopathic Parkinson’s…Biomarker based on natural language processing methods to detect the stages of Parkinson’s disease through electroencephalography
Objective: Stage classification of Parkinson's Disease (PD) through Electroencephalograms (EEGs) using Natural Language Processing (NLP) techniques. Background: PD is a neurodegenerative disease mainly characterized by…Effect of levodopa-carbidopa intestinal gel on lower urinary tract symptoms in Parkinson’s disease: an Urodynamic study
Objective: Here we report urodynamic results before and six months after LCIG treatment in PD patients suffering from LUTS. Background: Dopaminergic transmission plays a key…Height and nigral neuron density in Parkinson’s disease
Objective: To investigate the possible relationship between height and the density of neurons in the substantia nigra pars compacta (SNc). Background: The dopaminergic system modulates…Cortical oscillatory feature-based classification of Parkinson’s disease with freezing gait
Objective: The objective of this study was to determine the resting-state cortical oscillations and the machine learning model that best classifies Parkinson’s disease (PD) patients…Longitudinal predictors of functional dependence in a multicentric Parkinson’s Disease cohort
Objective: To explore clinical and cognitive predictors of functional dependence in a cohort of early Parkinson’s Disease (PD) patients. Background: Parkinson’s Disease (PD) patients are…
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