mGlu3 receptors in Parkinson’s disease as a candidate target for neuroprotective therapy: evidence from preclinical studies to human genetic.
Objective: In a toxicological model of mouse parkinsonism through chronic injection of MPTP, we examined whether the presence or absence of mGlu3 receptors affected neurodegeneration…Spinal cord stimulation for gait problems in Parkinson´s disease: Long term report and placebo viability
Objective: In the present study we set out to report a very long-term follow-up period of spinal cord stimulation (SCS) for Parkinson's Disease (PD) patients…Assessment of the long-term effects of STN-DBS on axial symptoms in PD patients through a standardized clinical-instrumental approach
Objective: To evaluate the long-term effects of bilateral STN-DBS and levodopa on axial symptoms in PD patients and the possible correlations between speech and gait…Dopamine neuron platform for screening molecular mechanisms and inhibitory drugs against alpha-synuclein aggregation
Objective: Optimization of a dopamine neuron based,in vitro platform is beneficial for studying molecular mechanisms of alpha-synuclein aggregation,and screening of inhibitory drugs and deducing their…The reliability and validity of the Ziegler test for measuring freezing of gait in people with Parkinson’s disease.
Objective: To determine the inter-rater and test-retest reliability of the Ziegler test to measure freezing of gait (FOG) severity in people with Parkinson’s disease (PwPD).…GPi-DBS induced brain metabolic activation in cervical dystonia
Objective: To investigate the effects of GPi-DBS on brain glucose metabolism locally at the stimulation site and across the whole brain in patients with cervical…Relationship between cholinergic basal forebrain volume and short-latency sensory afferent inhibition in Parkinson’s disease with varying degrees of cognitive performance
Objective: To assess the relationship between volumetric measures of cholinergic basal forebrain (CBF) degeneration and short-latency sensory afferent inhibition (SAI) in Parkinson’s disease (PD). Background:…Electrical stimulation of muscle afferents for tremor reduction in essential tremor patients
Objective: To describe the preliminary clinical results of a research project on electrical stimulation of muscle afferents to reduce tremor in patients with Essential Tremor…Impact of DBS on cognitive functions in Parkinson’s disease in 1 year follow-up
Objective: The aim of our study was to compare performance in neuropsychology tests in patients with Parkinson’s disease (PD) with implanted electrodes of Deep Brain…Genetic landscape of dystonia in Asian Indian patients
Objective: To identify potentially pathogenic genomic variations associated with dystonia phenotypes in Asian Indian patients with dystonia. Background: The Asian Indian population is underrepresented in…
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