Analysis of bilateral subthalamic nucleus deep brain stimulation in patients with monogenic forms of Parkinson’s disease: PRKN and LRRK2
Objective: The aim of this study is to compare the clinical and pharmacological response of bilateral STN DBS in patients with monogenic forms of PD…Effect of clinical levodopa medication cycle on subthalamic beta band power during therapeutic deep brain stimulation in Parkinson’s disease
Objective: To characterize the effect of levodopa medication cycle on subthalamic nucleus (STN) local field potential (LFP) beta-band power in Parkinson’s disease (PD) in the…Motor Fluctuations development is associated with non-motor symptoms burden progression in Parkinson´s disease patients. A 2-year follow-up study.
Objective: The aim of the present study was to analyze the progression of non-motor symptoms (NMS) burden in Parkinson´s disease (PD) patients regarding the development…Autonomic Nervous System Dysfunction in idiopathic REM sleep behaviour disorder
Objective: To characterise autonomic impairment in REM sleep behaviour disorders, and to investigate the pathophysiological link between autonomic impairment and REM sleep behaviour disorder Background:…Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.
Objective: To longitudinally assess presynaptic terminal loss in vivo over a 2-year period in people with early Parkinson’s disease (PD). Background: Imaging tools that allow…Long-Term Neuropsychological Outcomes of Deep Brain Stimulation in Early-Stage Parkinson’s Disease
Objective: To report long-term (5-year and 11-year) neuropsychological outcomes from the deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot clinical trial. Background: The…Updated Parkinson’s disease motor subtypes classification and correlation to CSF HVA and 5-HIAA levels
Objective: To update a motor subtypes classification using the MDS-UPDRS and determine if CSF neurotransmitter profiles (HVA and 5-HIAA) are different between MDS-UPDRS subtypes in…Functional MRI and gait analysis characteristics in patients with idiopathic rem sleep behavior disorder
Objective: The aims of this study were to assess gait analysis, neurological, neuropsychological and resting-state functional MRI (RS-fMRI) functional connectivity (FC) characteristics in iRBD patients…Longitudinal clinical and biomarkers characteristics of non-manifest LRRK2 G2019S carriers: The PPMI cohort
Objective: To examine 2-year longitudinal change in clinical, dopamine transporter (DAT) imaging and biofluid biomarkers in non-manifesting carriers (NMCs) of LRRK2 G2019S versus healthy controls…Longitudinal study of Parkinson’s disease-related pattern with resting state functional MRI
Objective: To validate the previously characterized resting-state fMRI (rs-fMRI) Parkinson’s disease (PD)-related pattern, termed fPDRP, in a large multi-site PD imaging database, and to assess…
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