CCDC88C p.R464H likely cause a novel late-onset parkinsonism phenotype
Objective: We describe two sisters with late-onset parkinsonism associated with a CCDC88C variant (p.R464H). Background: Tsoi et al. (2014) identified a heterozygous missense mutation in the CCDC88C gene (R464H), by…A Literature Review: Effectiveness of Transcranial Direct Current Stimulation on gait speed and freezing of gait in patients with Parkinson’s disease
Objective: The objective of this review is to update evidence on benefits of tDCS on gait speed and freezing of gait (FOG) for PD patients…Cerebellar sodium disequilibrium in a patient with ATP1A3-related rapid onset dystonia-parkinsonism
Objective: Here, we applied non-invasive 23Na Magnetic Resonance Imaging to study pathophysiology-related changes in the total and intracellular sodium content in a patient with rapid-onset…Prevention and management of Deep Brain Stimulation (DBS) surgical site infections (SSI) – multicentre survey of UK practice.
Objective: The aim of this survey was to better understand trends, patterns and practices of DBS surgical site care in the UK. Background: Deep brain…Alien hand syndrome in ischemic stroke: a case-report
Objective: Alien hand syndrome (AHS) is a rare movement disorder that inspires fear to patients and confuses doctors. So we describe a rare case-report. Background:…The Journey Of Levodopa Treatment in Parkinson’s disease
Objective: This study aims to relook the journey of levodopa in the treatment of Parkinson’s disease. Background: Levodopa has been used in the treatment of…Bitopertin, a GlyT1 inhibitor, attenuates the development of dyskinesia in the 6-OHDA-lesioned rat
Objective: To evaluate the effect of the glycine transporter 1 (GlyT1) inhibitor bitopertin at preventing dyskinesia development in the 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson’s…Real-World Treatment Patterns and Outcomes in Patients With Chorea Associated With Huntington Disease Using Tetrabenazine or Deutetrabenazine in Combination with Antipsychotic Drugs
Objective: To describe treatment patterns with vesicular monoamine transporter 2 inhibitors (VMAT2i; tetrabenazine [TBZ], or deutetrabenazine [DTBZ]) in combination with antipsychotic agents (APs) in patients…Detection of specific antigens in immune-mediated cerebellar ataxias
Objective: We aimed to clarify biomarkers and pathogenic autoantibodies in cerebellar ataxia, especially multiple system atrophy (MSA) and immune-mediated cerebellar ataxias (IMCAs), by detection of…COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.