Case reports of first experiences worldwide with novel continuous oral levodopa dental pump in Parkinson’s Disease Patients
Objective: To assess the safety, tolerability, and pharmacokinetics (PK) of a novel continuous levodopa-carbidopa oral pump (LCOP) delivery system in patients with early PD. Background:…Endocannabinoid Dysfunction in Human Disease: Neuro-Ocular DAGLA-related Syndrome (NODrS), a unique pediatric condition
Objective: To define a new pediatric movement disorder and conclusively link the endocannabinoid system to human disease. Background: The endocannabinoid system is a highly conserved…Metagenomic exploration of the gut microbiome in a sibling-controlled pilot study of children with Tourette Syndrome
Objective: To detect gut microbial signatures of Tourette syndrome (TS) in the first sibling-controlled investigation of this condition. Background: The contribution of gut microbiome, and…CLINICAL AND GENEOLOGICAL FEATURES OF PARKINSON’S DISEASE
Objective: The initial purpose of the work is to study the clinical and genealogical features of Parkinson's disease. Background: Currently, clinical genetics has a number…DUtch PARkinson Cohort (DUPARC): Contrast Sensitivity and Retinal Changes in Early Parkinson’s Disease Patients
Objective: To identify and characterize the correlation between static contrast sensitivity (SCS), dynamic contrast sensitivity (DCS), and thickness of the internal plexiform layer (IPL) in…Long-term safety of continuous levodopa/carbidopa infusion with ND0612: Data from patients who continued past one year in the BeyoND study
Objective: To report long-term safety and tolerability data from the ongoing BeyoND study (NCT02726386) for patients who continued treatment past the one-year primary endpoint. Background:…Dopamine-independent cortical disinhibition in Parkinson’s disease
Objective: To test the hypothesis that cortical disinhibition in Parkinson's disease is a dopamine-independent process. Background: Motor cortex alterations in Parkinson's disease are classically considered…Cortical and cerebellar excitability in essential tremor
Objective: To investigate the functional state of motor cortex excitability and the involvement of the cerebello-thalamo-cortical pathway using transcranial magnetic stimulation (TMS) in patients with…Delayed post-stroke parkinsonism: description of two cases and possible mechanism
Objective: To present two patients who developed delayed parkinsonism years after experiencing midbrain strokes and to suggest a possible mechanism for this delayed phenomenon. Background:…THE EFFECT OF DEEP BRAIN STIMULATION ON LOWER URINARY TRACT SYMPTOMS IN PARKINSON’S DISEASE
Objective: To evaluate lower urinary tract symptoms between Parkinson’s Disease (PD) patients with and without deep brain stimulation (DBS). Background: Parkinson's disease (PD) is well…
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