Feasibility of in-person and remote delivery of Alexander technique course for care partners of people with neurodegenerative disease
Objective: Test feasibility of in-person and remote delivery via Zoom of Alexander technique (AT) course to improve quality of life for care partners (CP) of…Therapeutic approach to botulinum injections for hemifacial spasm, post facial paralysis synkinesis and blepharospasm
Objective: To show our therapeutic outcome of botulinum injection to the facial muscles and thereby to find the best therapeutic concept which should be embraced.…miR-218-5p Regulates Microglia-mediated Neuroinflammation through Type I Interferon Response in Parkinson’s Disease
Objective: To explore the effect of miR-218-5p on microglia activation and dopaminergic neurons damage in mice model of Parkinson's disease(PD) and its potential mechanisms. Background:…Cerebellar transcranial direct current stimulation in spinocerebellar ataxia type 3: a randomized, double-blind, sham-controlled trial
Objective: To investigate if a 2-week regimen comprising daily sessions of cerebellar anodal transcranial direct current stimulation (tDCS) 1) diminishes ataxia and non-motor symptom severity…Synaptic density in cortical and subcortical gray matter is associated with mild parkinsonian signs (MPS) in healthy older adults: a [11C] UCB-J PET study
Objective: to investigate if a reduction in cortical and subcortical synaptic density measured in vivo with the synaptic vesicle protein 2A (SV2A) binding [11C] UCB-J…Within patient comparison of neurostimulator longevity; sequentially contrasting the Medtronic Activa PC to the Medtronic Percept PC utilizing in-device battery estimates
Objective: To examine the differences between Actual Activa PC longevity and the estimated longevity of the Percept PC, utilizing identical contact configurations and programming parameters.…Retinal vascular change of Parkinson’s disease patients with orthostatic hypotension
Objective: In the present study, we investigated difference of microvasculature of Parkinson’s disease (PD) patients with orthostatic hypotension (OH) and without OH, using optical coherence…Machine learning algorithms for classification and analysis of pen-on-paper Archimedes spirals
Objective: To classify tremor syndromes from freely hand drawn pen-on-paper Archimedes spirals using classical machine learning techniques. Background: Spiral drawings (Archimedean) are commonly used in…CCL5 promotes Th17 migrating into SNpc by promoting Th17 proportion increase and LFA-1 expression
Objective: To explore the specific pathway by which CCL5 induces Th17 cells migrating into substantia nigra pars compacta (SNpc) to aggravate Parkinson's disease (PD). Background:…Inflammatory microglial and astroglial phenotype associated with pathological alpha-synuclein inclusions in the substantia nigra
Objective: To characterize neuroinflammatory gene expression in microglia and astrocytes associated with early alpha-synuclein (a-syn) inclusion formation. Background: Parkinson’s disease (PD) is characterized by alpha-synuclein…
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