Non-motor symptoms in de-novo adult-onset focal dystonia
Objective: To assess the prevalence of non-motor symptoms in untreated de-novo patients with cervical dystonia and blepharospasm. Background: Adult-onset focal dystonia is a movement disorder…Meta-optimization to select stimulation settings for deep brain stimulation in Parkinson’s disease
Objective: The objective is to develop an algorithmic approach for selecting deep brain stimulation (DBS) settings for Parkinson’s disease (PD) and other movement disorders more…Reversible chorea due to bilateral basal ganglia lesion in diabetic uremic patient
Objective: To report diabetic patient with chronic renal failure who developed sudden chorea movements associated with reversible bilateral basal ganglia lesion. Background: Acute movement disorder…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…Clove mediated Rescue in Parkinson’s Disease involves modulation of p53 and Sestrin2 in SHSY5Y cell line model
Objective: The study analyzed the neuroprotective effect of ethanolic extract of clove against Parkinson’s disease (PD) type toxicity in SHSY5Y cell line model and interrogation…Caregiver burden in Parkinson’s Disease patients with Cardiovascular Dysautonomia
Objective: We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular…A Potential Cluster Near Site of Dry Cleaning Contamination
Objective: To characterize specific health outcomes of people with potential exposure to chemicals used in dry cleaning. Background: Trichloroethylene (TCE) is a chlorinated solvent used…Tissue Frataxin Increases After Administration of CTI-1601, a Frataxin Replacement Therapy in Development for the Treatment of Friedreich’s Ataxia
Objective: To evaluate the pharmacodynamic (PD) and safety profiles of subcutaneous (SC) administration of multiple ascending doses of CTI-1601 in patients age ≥18 years with…Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…Autonomic dysfunction and its correlation witn synucleinopathy: an immunohistological study in Tunisian patients with parkinson disease
Objective: Identify autonomic digestive symptoms of Parkinson disease (PD)Identify correlations between autonomic dysfunction and alpha-synuclein immunochemical staining in the upper digestive tract. Background: Pathological processes…
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