Assessment of novel diffusion MRI metrics of cortical microstructure in the genetic continuum of Parkinson’s disease
Objective: To investigate novel cortical diffusivity metrics in Parkinson’s disease (PD), including both prodromal and established genetic PD, alongside sporadic PD and healthy controls (HC).…Capturing the complexity of patients with parkinsonism: Baseline characteristics of participants in the PRIME-UK cross-sectional study
Objective: This cross-sectional study seeks to describe the symptomatology and health needs of a representative sample of people with parkinsonism, including those living with frailty,…Illusory responses across the Lewy body disease spectrum
Objective: To study pareidolias in patients across the Lewy body disease-spectrum, including those without psychosis. Background: Pareidolias are specific illusions of faces and objects perceived…Dopaminergic medication improves movement vigour in Parkinson’s but not the adaptation of movement speed to curvature
Objective: This study assessed kinematic profiles of individuals with Parkinson’s on and off dopaminergic medication to investigate whether the effect of dopaminergic modulation on speed…Gerstmann-Sträussler-Scheinker disease presenting as dystonia
Objective: Gerstmann-Sträussler-Scheinker disease (GSS) is a type of human transmissible spongiform encephalopathy that is determined genetically. Background: Gerstmann-Sträussler-Scheinker disease (GSS) is a type of human…Determination of glycine transporter 1 levels with [3H]-NFPS binding in hemi-parkinsonian rats with L-DOPA induced dyskinesia
Objective: To determine the distribution of the glycine transporter 1 (GlyT1) in brain areas implicated in parkinsonism and L-3,4-dihydroxyphenylalanine (L-DOPA) induced dyskinesia in the 6-hydroxydopamine…Women with Parkinson’s Disease (PD) and High Coffee Use Have a Shorter Time to Medication Initiation
Objective: Investigate how coffee use prior to PD diagnosis affects medication initiation in PD. Background: Population studies show a decreased incidence of PD for men…The REONPARK (REgistry of the use of COMT-inhibitors in the maNagement of patients with PARKinson’s disease in Spain who present early motor fluctuations) study: rationale and design of a national, multicentre and prospective study
Objective: To describe the real-world use of catechol-O-methyltransferase (COMT) inhibitors add on to levodopa/dopa decarboxylase inhibitor (DDCI) in patients with Parkinson’s disease (PD) suffering from…iFall: Usability of a co-produced falls reporting smartphone application in people with Parkinson’s
Objective: To assess the usability of a co-produced smartphone application for falls reporting in people with Parkinson’s (PwP) Background: Falls commonly occur in PwP, which…No association between naturally occurring plasma tau autoantibodies and movement disorders
Objective: To determine if there is an association between the presence of naturally occurring plasma tau autoantibodies and a movement disorder diagnosis. Background: The microtubule-associated…
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