Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Levodopa-carbidopa intestinal gel (LCIG) as an add-on therapy to deep brain stimulation (DBS) for managing progressive symptoms of advanced idiopathic Parkinson’s disease during the COVID-19 pandemic: Case Report
Objective: To report the use of levodopa-carbidopa intestinal gel (LCIG) as an additional therapy for the treatment of motor fluctuations in a patient with advanced…Impulse Control Disorders Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial
Objective: To assess the frequency and outcomes of impulsivity in study participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for the treatment of Parkinson’s Disease…Modulation of the mesencephalic locomotor region activity during gait in parkinson’s disease patients
Objective: Deciphering the role of the MLR in gait and balance disorders in PD patients Background: Lesion or dysfunction of the MLR, including the Pedunculopontine…Two Different Clinical Presentations in SYNE1 Ataxia in Turkey
Objective: SYNE1 (Spectrin repeat-containing nuclear envelope protein 1) gene mutation, first diagnosed in French Canadians in 2007, is now reported from many regions around the…ACUTE MOVEMENT DISORDERS: A NEW ASPECT OF SARS-COV2 INFECTION IN CHILDREN
Objective: To analyze the clinical aspects, radiological features and evolution of COVID-19-associated movement disorders (MD) in children and adolescents. Background: During the 5th wave of…Word association in Parkinson’s Disease using action verbs and emotion verbs
Objective: To investigate how the word association in patients with Parkinson’s disease (PD) is changed compared to a control group to obtain evidence on impairments…Variability of Plasma Levodopa Conveniently Reduced by More Frequent Administration of Smaller Doses of Carbidopa/Levodopa Using a Novel Functionally Scored Formulation
Objective: To evaluate the pharmacokinetics (PK) of 25/100 mg carbidopa (CD)/levodopa (LD) compared to half that amount given twice as often using a new, deeply…Disease knowledge in males and females with Parkinson’s Disease and Related Disorders
Objective: To examine sex differences in the knowledge base of Parkinson’s Disease and Related Disorders (PDRD) Background: Biologic sex accounts for differences in PDRD, not…Combining intraoperative microelectrode recordings with postoperative transcranial B-mode sonography of the brainstem to estimate the anatomical position of the electrode for chronic subthalamic nucleus deep brain stimulation in Parkinson´s disease
Objective: We tested whether the position of the electrode for deep brain stimulation (DBS) could be assessed relative to subthalamic nucleus (STN) dorsal boundaries by…
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