An automated AI-based framework for putamen volume measurement in MSA
Objective: The putamen is a difficult structure to segment accurately, and automated methods require manual editing to improve segmentation accuracy. Our aim was to test…De novo mutation in TMEM151A and Paroxysmal Kinesigenic Dyskinesia
Objective: To confirm the association between TMEM151A mutation and paroxysmal kinesigenic dyskinesia. Background: Heterozygous mutations in TMEM151A, encoding a protein of undetermined function, have been…Classification of extremity movements by visual observation of signal transforms
Objective: To create a tool for raters certified in the MDS-UPDRS) [1] to blindly score online signal transforms of the output of the wearable sensors to…Newly identified cases of parkinsonism and prodromal PD in a remote LRRK2 G2019S cohort
Objective: To evaluate new cases of prodromal PD and concern for parkinsonism in a cohort of LRRK2 G2019S carriers. Background: LRRK2 G2019S is a common…Clinical Characteristics of patients with Parkinson’s disease showing normal values on SBR in the DAT SPECT
Objective: The aim of this study was to clarify what the ‘normal’ values of the specific binding ratio (SBR), a measure of striatal radiotracer uptake…Telemedicine in a Himalayan country: unlocking the barrier in the management of Parkinson’s Disease
Objective: To evaluate the feasibility of telemedicine among PD patients in Nepal. Background: Nepal is a mountainous country occupying about 85% by Himalayas and hills…IPX203 dose conversion from immediate-release carbidopa-levodopa, in Parkinson’s disease patients with motor fluctuations.
Objective: To analyze dosing regimen data from a Phase 3 study in order to identify an optimal dose conversion from IR CD-LD to IPX203 for…Correlation between clinical scales and gait in Parkinson’s disease
Objective: The objective of this study is to verify the correlations between cognitive and motor clinical scales and gait in individuals with PD and whether…Prospective, Multicenter, Real-World Outcomes Study with Directional Deep Brain Stimulation Systems in the Treatment of Parkinson’s Disease
Objective: We present preliminary outcomes from an ongoing prospective, on-label, multicenter outcomes study conducted in the United States of patients with directional Deep Brain Stimulation…Comparison of efficacy and safety of adjunct treatments to levodopa in patients with Parkinson’s disease and wearing-off: A network meta-analysis of randomized, double-blind trials
Objective: To determine the rankings for efficacy and tolerability of levodopa adjuncts in patients with Parkinson’s disease (PD) and wearing-off by network meta-analysis. Background: When…
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