Patient-specific multivariate gray matter volumetric distance to predict disease severity in Parkinson’s disease
Objective: Identifying novel biomarkers to predict disease progression is of paramount importance in patients with Parkinson’s disease (PD). In this study, we utilized Structural Magnetic…Structural MRI prediction of freezing of gait in Parkinson’s disease after deep brain stimulation
Objective: 1) To describe the evolution of FOG in a large cohort of patients at 1 year postoperatively from bilateral STN-DBS in PD. 2) To…Intermediate cardiac denervation in early Parkinson’s disease
Objective: This study is aimed to evaluate the longitudinal associations between cardiac sympathetic denervation and cognitive status in Parkinson’s disease (PD). Background: There lacks an…Developing zebrafish CRISPR/Cas9 knockout models of Parkinson’s Disease to identify novel therapeutic targets.
Objective: Human patients present punctual mutations and/or small deletions in genes that have been associated with Parkinson’s disease, namely, park1, park2, park6, park7, and park8.…Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Levodopa-carbidopa intestinal gel (LCIG) as an add-on therapy to deep brain stimulation (DBS) for managing progressive symptoms of advanced idiopathic Parkinson’s disease during the COVID-19 pandemic: Case Report
Objective: To report the use of levodopa-carbidopa intestinal gel (LCIG) as an additional therapy for the treatment of motor fluctuations in a patient with advanced…Impulse Control Disorders Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial
Objective: To assess the frequency and outcomes of impulsivity in study participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for the treatment of Parkinson’s Disease…Modulation of the mesencephalic locomotor region activity during gait in parkinson’s disease patients
Objective: Deciphering the role of the MLR in gait and balance disorders in PD patients Background: Lesion or dysfunction of the MLR, including the Pedunculopontine…Two Different Clinical Presentations in SYNE1 Ataxia in Turkey
Objective: SYNE1 (Spectrin repeat-containing nuclear envelope protein 1) gene mutation, first diagnosed in French Canadians in 2007, is now reported from many regions around the…ACUTE MOVEMENT DISORDERS: A NEW ASPECT OF SARS-COV2 INFECTION IN CHILDREN
Objective: To analyze the clinical aspects, radiological features and evolution of COVID-19-associated movement disorders (MD) in children and adolescents. Background: During the 5th wave of…
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