Genetic and functional analysis of CCDC88C mutations in patients with Parkinson’s disease.
Objective: To investigate the association between rare deleterious CCDC88C variants and PD. Background: SCA40 is a rare form of spinocerebellar ataxia caused by heterozygous mutations…Double trouble: dystonic tremor due to FXTAS in a SCA1 family
Objective: To describe a patient belonging to a SCA1 family, who presented with action tremor and dysmetria but with a different genetic etiology. Background: Spino-Cerebellar…Apathy in Parkinson’s disease: Relation to autonomic symptoms
Objective: Our overall goal was to learn whether apathy would be associated with autonomic symptoms in Parkinson’s disease (PD). We examined whether a) PD patients…Therapy-associated risk decision making in individuals with multiple system atrophy and Parkinson’s disease, THE YAMSA TRIAL
Objective: This study aimed to quantify the risk willingness of patients suffering from the α-synucleinopathies multiple system atrophy (MSA) and Parkinson's Disease (PD) and identify…Is a Parkinson’s Sialorrhoea service effective?
Objective: Evaluate the efficacy and tolerance of Botulinum Toxin A (BoNT A) in managing sialorrhoea in People with Parkinsons (PwP)Assess impact on quality of life…Prevalence and clinical characteristics of young onset Parkinson’s Disease among Nepalese Population
Objective: To know the prevalence and clinical characteristics of young onset Parkinson’s Disease among Nepalese Population Background: Parkinson’s disease (PD) is a neurodegenerative disease which…“Grab-the-lock test “ – A novel clinical test for identification of dorsolateral Subthalamic nucleus [STN] during deep brain stimulation [DBS]
Objective: The target during STN DBS for Parkinson’s disease is the dorsolateral STN which plays a major role in motor functions in contrast to the venteromedial…Cued movement preparation and movement coding in human thalamic neurons
Objective: To study motor cognition in the human motor thalamus at the single cell and population level. Background: The motor thalamus, in particular its cerebellar-receiving…Safety and pharmacokinetics of anti-inflammatory NE3107 treatment in carbidopa/levodopa-treated patients with Parkinson’s disease: A phase 2a, double-blind, placebo-controlled study
Objective: To assess the safety, tolerability, and pharmacokinetics (PK) of NE3107 in carbidopa/levodopa (C/L)-treated patients with Parkinson’s disease (PD) Background: Disease-modifying therapies that augment the…The effect of levodopa on the blood activity of calpains in patients with Parkinson’s disease
Objective: To evaluate the effect of levodopa on the blood activity of calpains in patients with PD Background: Parkinson's disease (PD) is a chronic progressive…
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