Bradykinesia in Patients with Cervical Dystonia: Objective Assessment with Optical Sensor
Objective: To objectively quantify selected parameters of bradykinesia investigated by finger tapping in cervical dystonia patients using the Leap Motion Controller (LMC) sensor. Background: Bradykinesia,…Integrated analysis of phase 3 trials of foslevodopa/foscarbidopa demonstrated that majority of reported infusion site AEs including infections were non serious, mild to moderate in severity and did not result in treatment discontinuation.
Objective: To characterize reported infusion site infection adverse events (AEs) and their clinical management in patients with Parkinson’s disease (PD) treated with foslevodopa/foscarbidopa (LDP/CDP). Background:…Evaluating the efficacy of dextromethorphan/quinidine (DM/Q) in treating irritability in Huntington’s disease
Objective: To prove the efficacy and safety of dextromethorphan/quinidine 20mg/10mg (Nuedexta®) in patients with irritability due to HD. Background: Irritability is one of HD's most…Spectrum of Hereditary Spastic Paraparesis (HSP): A study from India
Objective: To explore the genetic spectrum of hereditary spastic paraparesis in Indian patients. Background: HSP belongs to a heterogenous group of monogenic neurological disorders with…Huntington’s disease patients with intermediate allele in Tunisia
Objective: To explore the clinical and molecular findings of two Tunisian patients with LOHD and carriers of an IA. Background: Huntington's disease (HD) is an autosomal…Childhood-onset writer’s cramp evolving to generalised dystonia –a new mutation in KMT2B gene
Objective: To present a case of childhood-onset dystonia with a new mutation in KMT2B gene. Background: KMT2B-related dystonia (DYT-KMT2B) is an increasingly recognized cause of…Stiff-Person Syndrome: Diagnosis and Experimental Models
Objective: Locked-in syndrome is a syndrome that is characterized by the lack of an adequate response of the patient to external, including verbal, stimuli due…Restless legs syndrome may be associated with freezing of gait, start hesitation and falls in Parkinson’s disease
Objective: We aimed to assess the association between RLS and freezing of gait, start hesitation and falls. Background: Parkinson’s disease (PD) is a neurodegenerative disease…Depression and Activities of Daily Living in Idiopathic Parkinson’s Disease without Dementia.
Objective: Objective: To study the influence of depression on ADLs in patients with PD in stages I and II of Hoenh and Yahr. Background: Background:…A case of idiopathic lower limb dystonia treated with combined use of botulinum toxin type A and phenol nerve block
Objective: Here we report a case of focal LLD successfully treated with combined botulinum neurotoxin type A (BoNTA) and Nerve block (NB). Background: Among focal dystonias,…
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