Characterization of gait variability of early Parkinson’s disease and multiple system atrophy
Objective: to determine the potential differences in gait characteristics between PD-GBA carriers and non-carriers (idiopathic Parkinson’s disease (iPD)), both mutually and in relation to MSA-P.…Internal tremor in Parkinson disease and essential tremor: a new glance at a common symptom
Objective: To assess the prevalence of internal tremor in a cohort of PD versus ET patients and its association with non-motor symptoms. Background: Internal tremor…PD-PROP reporting in participants own words shows high burden of cognitive symptoms in early Parkinson Disease (PD)
Objective: Describe the relative frequency of bothersome cognitive symptoms reported verbatim by people with PD in the Fox Insight online study. Background: Cognitive decline is…Caveats regarding a family with PD and LRRK2 mutations
Objective: To describe and discuss genetic considerations regarding a kindred with PD cases with similar clinical characteristics, some with identified mutations in the LRRK2 gene…Identification of atlastin genetic modifiers in a Hereditary Spastic Paraplegia model in Drosophila
Objective: To identify genetic modifiers of decreased locomotion and neuromuscular junction defects associated with atlastin knockdown in motor neurons. Background: Hereditary spastic paraplegias (HSPs) are…Are GDNF receptors the gatekeepers of GDNF efficacy during progressive nigrostriatal neuron loss?
Objective: To determine if GDNF receptor expression levels in the striatum or substantia nigra (SN) change in relation to differences in tyrosine hydroxylase (TH) and…Corticobasal Syndrome (CBS), Corticobasal Degeneration (CBD) and Progressive Supranuclear Palsy (PSP) Cohort in Central New York
Objective: Aims: The goal of this retrospective study was to characterize a CBS, CBD and PSP cohort and demonstrate that the Electronic Medical Record (EMR)…Transition among HD-ISS stages as an endpoint in clinical trials for HD
Objective: Investigate the time to the event of HD-ISS Stage 3 transition (functional change) as an endpoint for clinical trials in Huntington’s disease (HD) and…Diffusion Tensor Imaging of Spinocerebellar ataxia type 12 patients in comparison of Healthy control
Objective: To assess changes in brain tissue microstructures using diffusion tensor imaging parameters, fractional anisotropy (FA), increased radial (RD) and axial diffusivities (AD) in SCA…Characteristics of cases in which stimulation was programmed for multiple targets in deep brain stimulation therapy for Parkinson’s disease.
Objective: To clarify the the clinical background of Parkinson's disease patients with DBS who received multiple stimulus targets. Background: Deep brain stimulation (DBS) is an…
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