Identification of xylopropamine as a potential dopamine D2 receptor agonist through computational drug discovery pipeline
Objective: This study aims to identify novel dopamine D2 receptor agonists through the computational drug discovery pipeline. Background: Parkinson's disease (PD) is a neurodegenerative disorder…Accelerated longitudinal brain atrophy in the ‘diffuse malignant’ Parkinson’s disease subtype
Objective: To investigate differential pattern of brain atrophy between Parkinson’s disease (PD) clinical subtypes using longitudinally acquired brain magnetic resonance imaging (MRIs). Background: Parkinson’s disease…At-home adaptive deep brain stimulation improves motor fluctuations and quality of life in patients with Parkinson’s disease: a single-blind randomized study
Objective: We evaluated the effect of at-home adaptive deep brain stimulation (aDBS) based on personalized neural biomarkers on motor symptoms and quality of life (QoL)…VPS11 associated movement disorder in a pediatric case
Objective: Disorders of intracellular trafficking may present with different neurological features such as pediatric movement disorders. Background: A 15-year-old boy presented with a three-year history…Pain and moods disorders as determinants of quality of life in Parkinson
Objective: Correlation of non-motor symptoms such as pain, anxiety, and depression in the quality of life and severity of the disease in patients living with…Movement disorders in children with progressive myoclonic epilepsies
Objective: To analyze the clinical aspects, radiological features and evolution of myoclonus and other movement disorders (MD) in children with progressive myoclonic epilepsies (PMEs). Background:…Factors influencing voice function after deep brain stimulation in Parkinson’s disease
Objective: To assess the effect of Deep Brain Stimulation (DBS) on self-perceived changes of voice function in Parkinson’s disease (PD). Background: To date, the effect…Association between type 2 diabetes mellitus with parkinson’s disease and the increase of the severity of depression and anxiety in a mexican population
Objective: To compare the severity of depression and anxiety in PwP between those with T2D and those without T2D. Background: Parkinson's disease (PD) is the…Nonketotic hyperglycemia-induced hemichorea/hemiballism in El Salvador: A case Series
Objective: We conducted a retrospective study to investigate the clinical characteristics of patients with nonketotic hyperglycemia-induced hemichorea/hemiballism referred to a movement disorder clinic in El…Words Spoken Daily: A Novel Measure of Cognition
Objective: To assess the average number of words spoken per day by individuals with Parkinson’s disease (PD), mild cognitive impairment (MCI), and control participants. Background:…
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