Clinical implication of small vessel disease burden on deep brain stimulation outcome in Parkinson’s disease
Objective: We aimed to investigate the correlation between the small vessel disease (SVD) burden and the 1-year outcome after the globus pallidus interna (GPi) deep…Gender-Specific Classification Models for Parkinson’s Disease using Non-Motor Symptoms and DNA Methylation Data
Objective: In Parkinson's disease (PD) non-motor symptoms often appear before the motor symptoms. Detecting and understanding these non-motor symptoms and their possible genetic or epigenetic…Monoamine loss and depression in Parkinson’s disease: a PET study
Objective: 1)To evaluate the imaging manifestations of monoamine changes in PD patients with depression through 18F-FP-DTBZ PET; 2) To explore the relationship between monoamine changes…Validation of the EQ-5D-3L in Spinocerebellar Ataxia (SCA)
Objective: Our study aims to assess the acceptability, validity and responsiveness of the EQ-5D-3L in SCA types 1, 2, 3 and 6. Background: Although health-related…Structural MRI and tremor analysis in the differential diagnosis of rest tremor
Objective: This study aimed to differentiate between essential tremor with rest tremor (rET) and tremor-dominant Parkinson’s disease (td-PD) patients through a machine learning (ML) approach…Early functional disruption in body-first compared to brain-first Parkinson’s disease
Objective: To analyze differences in functional connectivity (FC) between Parkinson’s disease (PD) patients with and without premotor REM behavior disorder (pRBD), by means of high-density…Risk factors for Freezing of Gait in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: To comprehensively identify risk factors of freezing of gait (FOG) in Parkinson’s disease (PD), we performed a meta-analysis by combining the results of previous…Role of ATP10B variants in Parkinson Disease in a southern Spanish cohort
Objective: The objective of our study was to evaluate the role of ATP10B variants in Parkinson disease (PD) in a southern Spanish cohort of PD…Late-onset cerebellar ataxia revealing a Pantothenate-kinase-associated neurodegeneration
Objective: Recall a case of genetic late-onset cerebellar ataxia with a specific clinical and radiological feature highly suggestive of Pantothenate-kinase-associated neurodegeneration(PKAN). Background: Cerebellar ataxia is…Impaired Nt-acetylation and the Golgi, a new disease mechanism leading to autosomal recessive primary familial brain calcifications
Objective: To identify new disease-gene in unsolved autosomal recessive primary familial brain calcifications. Background: Primary familial brain calcification (PFBC) is characterized by calcium deposition in the brain,…
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