Clinical usefulness of tandem gait test for estimating gait and balance in de novo Parkinson’s disease
Objective: The purpose of this study is to objectively evaluate the gait and balance in patients with Parkinson’s disease showing abnormal tandem gait, using three-dimensional motion analysis.…Modeling Parkinson’s disease progression accounting for the effect of symptomatic treatments in the Parkinson’s Progression Markers Initiative study
Objective: To explore the natural history of Parkinson’s disease (PD) accounting for the effect of symptomatic treatments on progression by modeling the time course of…Anle138b-P1-02: A randomised, double-blinded, placebo-controlled phase 1b study to investigate safety, tolerability, pharmacokinetics and pharmacodynamics of the oligomer modulator anle138b in Parkinson´s disease
Objective: To present first-in-patient data of the oligomer modulator anle138b (TEV-56286, emrusolmin) in patients with Parkinson’s disease (PD). Background: Synucleinopathies such as PD and Multiple…Clinical characteristics of patients with dementia with Lewy bodies followed in a movement disorder clinic
Objective: To describe the clinical phenotype of the subgroup of patients with Dementia with Lewy bodies (DLB) followed in a movement disorder setting rather than…Asymmetry and the development of phase-specific deep brain stimulation for essential tremor
Objective: The main aim of the study was to investigate asymmetry in ET and the association between tremor asymmetry and the effect of DBS on…Identification of a Metabolic Brain Pattern Specific to Corticobasal Degeneration and Its Utility in Differential Diagnosis
Objective: To identify a metabolic brain pattern specific to corticobasal degeneration (CBD) and to develop a machine learning algorithm that can differentiate CBD from other…Clinical and radiological factors associated with mortality in Parkinson’s disease
Objective: To assess clinical and radiological risk factors of mortality in a cohort of patients with a clinical diagnosis of Parkinson’s disease (PD) according to…Polyneuropathy in Parkinson’s disease: cross-sectional analysis of the Bochum Parkinson Nerve Study cohort
Objective: To describe the prevalence of large-fiber polyneuropathy (PNP) in people with PD and examine differences between subjects with or without PNP. Background: Non-motor symptoms…Retrospective exploration of the 5-2-1 criteria in clinical practice
Objective: To explore documentation in medical records (EMRs) of the 5 (5 oral levodopa doses taken/day) -2 (2hours of OFF time/day) -1 (1 hour of…Axial impairment and bradykinesia are related to increased CSF sTREM2, a neuroinflammation biomarker, in Parkinson’s disease
Objective: To explore the association between Parkinson’s disease (PD) motor symptoms and CSF biomarkers for neuroinflammation and neurodegeneration. Background: Previous in vivo and post mortem…
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