MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    Clinical and genetic profile of fifteen patients with PARK-PRKN: A largest single-center cohort from India.

    V. Holla, S. Kamath, P. Phulpagar, N. Kamble, B. Muthusamy, R. Yadav, P. Pal (Bengaluru, India)

    Objective: To study the clinico-genetic profile of patients with genetically proven parkinsonism secondary to biallelic variants in PRKN gene (PARK-PRKN). Background: PARK-PRKN is the most…
  • 2023 International Congress

    Relationship between balance performance and corticomotor Inhibition in individuals with Parkinson’s disease

    HH. Liu, YR. Yang, YL. Ling, RY. Wang, SJ. Cheng (Taipei City, Taiwan)

    Objective: To explore the possible relationship between corticomotor inhibition assessed by transcranial magnetic stimulation (TMS) and balance performance in individuals with Parkinson’s disease (PD). Also,…
  • 2023 International Congress

    Image-guided programing in useful in DBS for Parkinson’s disease

    S. Marmol, J. Moll, H. Bullock, I. Haq, J. Jagid, C. Luca (Miami, USA)

    Objective: To evaluate the utility of image-guided DBS programming; to determine the correlation between optimal DBS electrode placement predicted by imaging-guided software and monopolar review…
  • 2023 International Congress

    Tramadol Induces Neuroinflammation, Mitochondrial Oxidative Stress, Neurotransmitters Dysbalanced and Produced Parkinson’s Disease Like Symptoms in Experimental Wistar Rats

    KHA. Aran (Moga, India)

    Objective: The current study is designed to evaluate the possible neurotoxic effects of tramadol in Wistar rats. Background: Parkinson’s disease (PD) is a chronic neurodegenerative…
  • 2023 International Congress

    A staged screening paradigm to identify people at risk of Parkinson’s disease in the Parkinson’s Progression Markers Initiative

    E. Brown, A. Siderowf, T. Simuni, T. Sherer, M. Brumm, C. Caspell-Garcia, R. Kurth, C. Gochanour, M. Kuhl, M. Korell, J. Valverde Twiggs, C. Stanley, L. Concha, C. Soto, K. Marek, C. Tanner (San Francisco, USA)

    Objective: To identify people at risk of Parkinson’s disease (PD) using a staged-screening paradigm. Background: Early recognition of people with PD may be essential to…
  • 2023 International Congress

    A white matter disease with blooming grey matter

    K. Kanojia, F. Mustafa, P. Mohapatra, A. Srivastava, D. Radhakrishnan (New delhi, India)

    Objective: To describe a case of LMNB1-related autosomal dominant leukodystrophy with unique radiological features. Background: Autosomal dominant leukodystrophy (ADLD), caused by the duplication of the…
  • 2023 International Congress

    Ramelteon ameliorates abnormal sleep-wake behavior in a zebrafish model of Parkinson’s disease by facilitating abnormal lipid metabolism

    F. Wang, MZ. Pang, JY. Liu, CF. Liu (Suzhou, China)

    Objective: The study aims to explore the role of melatonin receptor 1 (MT1) in the regulation of sleep-wake behavior in rotenone-induced Parkinson's disease (PD) model…
  • 2023 International Congress

    Long-term outcomes after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) in Singapore

    YZ. Cai, W. Li, Y. Zheng, A. Zhan, HL. Ng, Z. Xu, KY. Tay, WL. Au, L. Tan, WH. Ng, KR. Wan, S. Neo (Singapore, Singapore)

    Objective: To evaluate the long-term outcomes of subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) up to 10 years after surgery.…
  • 2023 International Congress

    Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD

    J. Li, J. Ruiz Tejeda, D. Tran, S. Nguyen, N. Phielipp (Irvine, USA)

    Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…
  • 2023 International Congress

    Impaired CaMKII/ERK activation in mouse mutant LRRK2 R1441G fibroblasts was associated with reduced mitochondrial calcium store and efflux in response to depolarization stress

    E. Chang, Y. Malki, Z. Choi, H. Liu, S. Zhang, S. Pang, M. Kung, D. Ramsden, S. Ho, P. Ho (Hong Kong, Hong Kong)

    Objective: To determine the molecular link of LRRK2R1441G mutation to impaired CaMKII/ERK signaling under mitochondrial depolarization stress using mutant mouse embryonic fibroblast (MEF) model of…
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