Does the dopaminergic pathway interfere with the sustained CSF tap test effect in normal-pressure hydrocephalus?
Objective: To discuss the possible dopaminergic pathway interference as a mechanism underlying the sustained benefit of the CSF tap test in NPH. Background: The sustained…Racial and Ethnic Differences in Suicidal Ideation in North American patients with Huntington’s Disease: Analysis using the ENROLL-HD Dataset
Objective: To identify racial and ethnic differences in history of suicidal ideation among Huntington’s Disease patients, using the ENROLL-HD, 2020 periodic dataset. Background: Suicidal ideation…Early-onset levodopa-responsive Parkinsonism associated with dysarthria, pyramidalism, and dystonia: a rare condition that can benefit from a combined treatment approach.
Objective: To describe a rare case of early-onset parkinsonism (EOP) successfully treated with a combined therapeutic approach. Background: EOP is a rare condition manifesting with…Botulinum neurotoxin in FXTAS-related tremor: a “successful” case report
Objective: We report the case of a man affected by FXTAS, presenting with disabling tremor who experienced a significant and long-lasting benefit from botulinum neurotoxin…A role of transcranial sonography in evaluating patients with dystonia and tremor
Objective: The objective of this study was to assess changes in transcranial sonography (TCS) in patients with focal dystonia (FD) with or without tremor and…Phenotypic presentation of essential tremor patients with Rapid eye movement disorder
Objective: To describe the prevalence of rapid eye movement disorder (RBD) among essential tremor (ET) patients and its correlates in terms of associated motor and…Identification of xylopropamine as a potential dopamine D2 receptor agonist through computational drug discovery pipeline
Objective: This study aims to identify novel dopamine D2 receptor agonists through the computational drug discovery pipeline. Background: Parkinson's disease (PD) is a neurodegenerative disorder…Accelerated longitudinal brain atrophy in the ‘diffuse malignant’ Parkinson’s disease subtype
Objective: To investigate differential pattern of brain atrophy between Parkinson’s disease (PD) clinical subtypes using longitudinally acquired brain magnetic resonance imaging (MRIs). Background: Parkinson’s disease…At-home adaptive deep brain stimulation improves motor fluctuations and quality of life in patients with Parkinson’s disease: a single-blind randomized study
Objective: We evaluated the effect of at-home adaptive deep brain stimulation (aDBS) based on personalized neural biomarkers on motor symptoms and quality of life (QoL)…VPS11 associated movement disorder in a pediatric case
Objective: Disorders of intracellular trafficking may present with different neurological features such as pediatric movement disorders. Background: A 15-year-old boy presented with a three-year history…
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