Development and quantified evaluation of a continuous smartphone app-based monitoring approach to individualize Parkinson’s disease management.
Objective: The aim of this study is the development and qualified evaluation of a smartphone app-based application to enable a longitudinal assessment of Parkinson’s disease…Insular dopamine deficits in prodromal α-synucleinopathies
Objective: aim of the study was to evaluate the dopamine binding characterizing subjects both at prodromal and symptomatic stages in α-synucleinopathies, by means of ROI-based…Short and long-term effects of deep brain stimulation on cognition in Parkinson’s disease
Objective: To evaluate long-term effects of subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease (PD) on cognition. Background: Cognitive changes are common among patients…Subthalamic stimulation reshapes the reliable inherent brain state in Parkinson’s disease
Objective: To elucidate the reliable inherent state of resting-state global brain network and explore the state modulation mechanism of subthalamic stimulation (STN-DBS) on Parkinson’s disease…SLP-2 modulated expression rescues mitochondrial function in alpha-synuclein neuropathology models
Objective: Validate the rescue potential of SLP-2 induction for α-synuclein (aSyn)-induced mitochondrial pathology and neurodegeneration in two complementary models: human induced pluripotent stem cell (hiPSC)-derived…Long-term effectiveness of adjuvant treatment with catechol-o-methyltransferase or monoamine oxidase B inhibitors compared with dopamine agonists in Parkinson’s disease uncontrolled by levodopa: final results of the PD MED LATER randomized clinical trial
Objective: PD MED LATER is a large, pragmatic trial aiming to determine which class of drug when added to levodopa provides the most effective control…Effects of a nurse-led Advance Care Planning and Care Coordination intervention in Parkinson’s Disease – patient and family caregiver perspectives from a multicentre European study
Objective: To investigate an Advance Care Planning (ACP) and care coordination intervention from the perspective of people with Parkinson's disease (PwPD) and their family caregivers…Transcriptional dysregulation in iPSC-derived neurons from patients with X-linked dystonia-parkinsonism
Objective: We pursue to identify dysregulated cellular pathways underlying X-linked dystonia-parkinsonism (XDP) by transcriptome profiling of induced pluripotent stem cell (iPSC)-derived neuronal cultures from XDP…Microbiota and Gastrointestinal Manifestations of Parkinson’s Disease with Arabic Translation of Gastrointestinal Dysfunction Scale
Objective: To investigate the frequency of occurrence of gastrointestinal tract GIT symptoms and their relation to patients’ clinical characteristics in addition the characteristics of gut…Exploring brain mechanisms of identity attribution in presence hallucinations of Parkinsonian origin
Objective: Study cognitive, behavioral correlates of identity of presence hallucinations in Parkinson’s disease. Background: Presence hallucination (PH), the sensation that someone is nearby when no…
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