Introducing the molecular subtyping of Progressive Supranuclear Palsy: a proof of concept
Objective: To enhance understanding of the molecular mechanisms underlying disease heterogeneity in Progressive supranuclear palsy (PSP) Background: PSP is a 4R-tauopathy characterised by subcortical pathology…Disease progression in multiple system atrophy: the value of clinical cohorts with long follow-up
Objective: To describe MSA progression according to the latent disease continuum and assess the value of long-term follow-up. Background: Although essential for therapeutic development, describing…Protective effect and mechanism of TREM2 in Parkinson’s disease with cognitive impairment
Objective: this study explored whether TREM2 plays a protective role in PD with cognitive impairment by promoting the activation of DAM. Background: The latest research…Characterization of at-home sleep macrostructure in Parkinson disease using a wearable sleep monitoring device
Objective: Determine the viability of a wearable reduced montage EEG device to record sleep in a population of patients with Parkinson disease (PD). Background: Sleep…Trajectories of Physical Performance in Prodromal and Early Parkinson’s Disease
Objective: To describe trajectories of physical performance in prodromal and early Parkinson’s Disease (PD). Background: There is a need to better characterize the prodromal and…Validation of a Remote Patient Monitoring System for Parkinson Symptom Severity
Objective: To evaluate the feasibility of building a remote patient monitoring (RPM) system for measuring Parkinson symptom severity. Background: The characteristic objective measures (tremor, rigidity,…Use of a wearable vibration-based device for the treatment of Parkinson’s disease tremor
Objective: To assess the use of a wearable vibration-based device for the treatment of Parkinson’s disease (PD) tremor. Background: PD is a neurodegenerative movement disorder…Brain functional state mapping in resting state and network alteration in Spinocerebellar Ataxia Type 2 in comparison with healthy controls
Objective: The aim of this study is to map the brain functional network alterations by estimating functional connectivity of brain structures in spinocerebellar ataxia type 2.…Preoperative trajectory planning is important to minimize intracerebral hemorrhage after deep brain stimulation, in comparison with ventricle peritoneal shunt.
Objective: We compared the occurrence of postoperative intracerebral hemorrhage (ICH) in deep brain stimulation (DBS) and ventricle peritoneal (VP) shunt at our institution. Background: Although…Effect of differences in stomach and small intestine pH on response to levodopa in patients with Parkinson’s Disease.
Objective: To examine levels of stomach and small intestine (SI) pH in relation to variable clinical responses to doses of levodopa in Parkinson’s disease (PD)…
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