Chronotropic incompetence – a possible marker of severe Parkinson’s disease phenotype?
Objective: Perform a retrospective analysis of patients with Parkinson’s disease (PD) who previously have undergone a cardiac stress test, with the aim of comparing clinical…The N6-Methyladenosine mRNA Methylase METTL14 Regulates TLR4-mediated intestinal dysfunction in Parkinson’s Disease
Objective: The aim of this study is to explore the function and mechanism of RNA m6A modification in gut-derived inflammation of Parkinson's disease (PD). Background:…Neurophysiological analysis of the posterior subthalamic area in a patient with Holmes’ tremor
Objective: To analyze the neuronal firing patterns in the posterior subthalamic area (PSA) in a Holmes’ tremor (HT) patient who underwent DBS implantation procedure. Background:…CBS presenting rapidly progressive anterior operculum syndrome with suggested background pathology of 4-repeat tauopathy by tau PET: A case report
Objective: Report of a case with suspected TDP-43 proteinopathy as the pathological background in the early stage of the disease, and a final diagnosis of…An investigation of early changes in the brain due to mild cognitive impairment in Parkinson’s disease
Objective: To identify baseline structural brain differences between individuals with Parkinson's disease (PD) who go on to develop mild cognitive impairment (PD-MCI) and those who…Clinical and genetic analyses of a Swedish patient series diagnosed with ataxia
Objective: In this study, we aimed to examine clinically and genetically a patient series with ataxia from southern Sweden with known or unknown genetic causes.…Opicapone’s Effects on Progression Scales in Relation to the 9-Symptom Wearing-off Questionnaire: the OPTIPARK Study
Objective: This study aims to evaluate changes in Parkinson’s disease (PD) progression scales in patients with PD and motor fluctuations (MF) treated with once-daily opicapone…Beta is jumping the queue: Temporal overlap of beta desynchronization and synchronization during rapid movement changes
Objective: Movement initiation and termination are often studied in isolation. Here we shed light on the neural processes underlying rapid changes of ongoing movements, where…Current practices for ‘timing’ of physical therapy in Parkinson’s Disease: ‘Burst vs. Spaced’
Objective: To assess current practices for timing of physical therapy (PT) in Parkinson’s disease (PD). Background: Most persons with Parkinson disease (PD) face increasing mobility…Clinical severity in Parkinson’s disease is determined by decline in cortical compensation
Objective: We tested whether inter- and intra-individual differences in clinical severity are determined by cortical compensation, and not just by basal ganglia dysfunction. Background: Motor…
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