Movement disorders in children with neurometabolic and neurodegenerative disorders: A single-center prospective study
Objective: To analyze the prevalence, patterns and severity of movement disorders in children with genetically proven neurometabolic and neurodegenerative diseases. Background: Movement disorders are often…Use of stimview technology in deep brain stimulation of Parkinson´s disease patients
Objective: We present our experience of Stimview technology in the neurostimulation of 5 patients with Parkinson´s disease (PD). Background: It is common to make adjustments…Non-intrusive Video-Based Solution for Continuous Quantitative Monitoring of Parkinson’s Patients’ Motor Functions
Objective: Feasibility and preliminary validation of a marker-less solution for automatic capture and quantification of movements during prespecified tasks of people with Parkinson’s (PwP) using…Custom-made Application Interface using Wacom® Tablet for Assessment of Writer’s Cramp
Objective: To evaluate a custom designed software platform to digitise handwriting data in writers cramp and normal controls. Background: Focal task specific dystonia occurring while…Evaluation of neuroprotective role of carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model
Objective: To explore the antioxidant and anti-inflammatory role of Carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model Background: NLRP3 inflammasome mediated neuroinflammation is…The long and short of contemporary parkinsonism survival: A 47-year clinicopathological study
Objective: We report a 47-year survival study of autopsy verified Parkinson syndrome (PS) and Parkinson’s disease (PD) cases. The objectives were: 1) to identify PS…Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: interim analysis of a pilot add-on, randomized, controlled, pragmatic clinical trial
Objective: This interim data analysis preliminarily evaluated the feasibility and effectiveness of protocolized CHM on motor-related daily living of PD patients. Background: A Chinese national…KINETIC 2: An ongoing phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor
Objective: KINETIC 2 (NCT05173012) is an ongoing, phase 2b, randomized, double-blind, placebo-controlled, dose-response study that aims to evaluate the efficacy, safety, and tolerability of SAGE-324/BIIB124…Foslevodopa/foscarbidopa subcutaneous infusion shows similar infusion site reaction severity score across range of infusion rates in patients with Parkinson’s disease
Objective: Characterize the relationship between foslevodopa/foscarbidopa infusion rate and infusion site reaction (ISR) score in patients with Parkinson’s disease (PD) Background: As PD progresses, motor…Feasibility and efficacy of a multidisciplinary telemedicine intervention program to reduce falls and gait impairment in Parkinson’s disease (NCT04694443).
Objective: To evaluate the feasibility and effectiveness of a multidisciplinary telemedicine intervention program to reduce falls and to improve quality of life (QoL) in patients…
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