The epigenetic association of Parkinson’s disease risk gene- GPNMB rs199347 with drinking
Objective: This paper examines the epigenetic association of rs199347 polymorphism variants of the GPNMB with drinking and DNA methylation changes. Background: Neuroinflammatory response induced by alcohol…Unsupervised physical capacity testing at home: a systematic review
Objective: Systematically review home-based physical capacity tests and their clinimetric properties in different patient populations with a chronic disease. Background: Physical capacity is a predictor…Does hyposmia induce apathy in early Parkinson’s disease? Lessons from structural brain connectivity
Objective: To study changes in microstructural integrity of white matter tracts associated with apathy in patients with early Parkinson’s disease (PD) and hyposmia Background: Smells…24(S)-Hydroxycholesterol and cognition in Huntington’s disease: results from two large patient cohorts (TRACK-HD and ENROLL-HD)
Objective: To investigate correlations between plasma levels of 24(S)-Hydroxycholesterol (24[S]-HC) and cognitive performance in participants with Huntington’s disease (HD) using data from ENROLL-HD. Background: HD…Impairment of SHH signaling in PD LRRK2 I1371V iPSC derived floor plate cells contribute to ontogenic origin of lower dopaminergic-neuron yield
Objective: To estimate SHH responsiveness & signaling of Floor Plate Cells (FPCs) derived from LRRK2 I1371V PD patient-iPSCs along with its link with LRRK2 I1371V…Nutritional traits in the prodromal phase on Parkinson’s disease in community-dwelling older adults in Japan
Objective: The objects of this study is to clarify the relationship between nutritional traits and the prodromal phase of PD in the community-dwelling older adults.…Effect of Recognition of Vertical Posture on Forward Bending Posture in Patients with Parkinson’s Disease: A Multicenter Observational Study
Objective: The mechanisms of postural abnormalities in Parkinson’s disease are diverse but often intractable, and there are no established measures to prevent early-stage progression. Background:…Introduction of a Parkinson’s Disease Virtual Ward Round
Objective: To introduce an electronic alert when people with Parkinson’s disease (PwP) are admitted to Sherwood Forest Hospitals NHS Trust (SFH). Background: PwP are more…On-demand therapy (ODT) in Parkinson’s disease: a survey of advanced practice providers
Objective: A survey of neurology Advanced Practice Providers (APPs) provides insights into their perspectives on managing and treating patients with Parkinson’s disease (PD) in the…Parkinson’s disease: cardiorespiratory fitness, respiratory muscle strength and lung capacity after a high-intensity Aquatic Physiotherapeutic Exercise Program (APEP/PEFA)
Objective: To compare cardiorespiratory fitness (CF), respiratory muscle strength and lung capacity (LC) after a high-intensity Aquatic Physiotherapeutic Exercise Program (APEP/PEFA). Background: Dopaminergic degeneration and…
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