Parkinson’s disease and human gut microbiota in an Egyptian population: a pilot study
Objective: The main objective of our research is to decipher the association between the gut microbiota and Parkinson's disease in an Egyptian cohort. Background: Parkinson’s…PD.ai – Detection of Parkinson’s Disease with gait-based biomarkers using AI techniques
Objective: This study evaluated the utility of Artificial Intelligence (AI) in detection of patients with Parkinson’s disease from stride dynamics. Background: Parkinson’s Disease (PD) is…Effects of cerebellar cTBS on motor symptoms in Huntington’s disease: a feasibility and pilot study
Objective: To evaluate the feasibility and preliminary clinical effects of a single session of cerebellar cTBS in patients with Huntington's disease (HD) with mild-moderate motor…Turning 360 degrees in standing – associations with perceived walking difficulties and comfortable gait speed in people with drug naïve/early Parkinson’s disease.
Objective: To investigate how turning performance (360 degrees in standing) is associated with perceived walking difficulties and comfortable gait speed in people with drug naïve…Regional Atrophy and Motor Speech in PSP
Objective: This study examined the association of regional atrophy on MRI and motor speech in PSP. Background: Motor speech impairment is common in PSP[1]. Although…Real-world effectiveness and safety of deutetrabenazine in patients with chorea associated with Huntington disease
Objective: To assess real-world effectiveness and safety of deutetrabenazine (DTBZ) for chorea associated with Huntington disease (HD). Background: Real-world evidence on the impact of DTBZ…Can radiofrequency lesion be better than DBS?
Objective: Pallidotomy represents a viable alternative for Parkinson disease(PD) symptoms treatment and has several important advantages, including a decreased need for access to specialists and clinical follow-up, improved affordability, and a lower infection risk, producing high long-term success rates and low morbidity rates. Background: Pallidotomy is recognized as effective for treating the symptoms of Parkinson's disease. Sometimes, radiofrequency may…Connectomics of Chronic VIM vs Rescue VIM/VO Deep Brain Stimulation in Essential Tremor
Objective: This study aims to use connectomic analysis to determine the difference between fiber pathway activation in patients with ineffective VIM stimulation and effective VIM/VO…Small Molecule Inhibitors for Precise Inhibition of α-Synuclein Oligomer Generation in Parkinson’s Disease (PD)
Objective: To develop small molecule therapeutics for PD that inhibit production of toxic α-synuclein oligomers and reduce aggregate formation, targeting the molecular mechanisms at the…Late Onset Cerebellar Ataxia in a Patient with a Heterozygous Pathogenic KIF1A Mutation: A Case Report
Objective: Expand upon the current phenotypic understanding of those with KIF1A-associated neurological disorder (KAND), including late onset progressive cerebellar ataxia (CA). Background: KAND encompasses a group…
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