MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    Safety of foslevodopa/foscarbidopa during optimization and maintenance treatment: Post hoc analysis of a phase 3, single-arm trial

    D. Kern, S. Isaacson, S. Dhanani, J. Aldred, B. Bergmans, D. Santos-Garcia, T. Oeda, F. Gandor, P. Kukreja, L. Bergmann, R. Gupta, S. Talapala, A. Spiegel, T. Kimber (Aurora, USA)

    Objective: Evaluate the frequency of adverse events over time with foslevodopa/foscarbidopa (LDP/CDP) in patients with advanced Parkinson’s disease (PD) in a phase 3, open-label safety…
  • 2023 International Congress

    Reproductive life factors and sex hormones in post-menopausal female patients with Parkinson’s Disease

    R. Bovenzi, M. Conti, G. Sancesario, R. Cerroni, M. Pierantozzi, A. Stefani, N. Mercuri, T. Schirinzi (Rome, Italy)

    Objective: To deepen into sex-dependent mechanisms of Parkinson’s disease (PD) by analyzing the relationships between reproductive life factors, sex hormones, clinical features, and CSF biomarkers…
  • 2023 International Congress

    The epigenetic association of Parkinson’s disease risk gene- GPNMB rs199347 with drinking

    YC. Chen, SL. Wu, YP. Liaw (Changhua, Taiwan)

    Objective: This paper examines the epigenetic association of rs199347 polymorphism variants of the GPNMB with drinking and DNA methylation changes. Background: Neuroinflammatory response induced by alcohol…
  • 2023 International Congress

    Unsupervised physical capacity testing at home: a systematic review

    D. de Graaf, S. Thissen, A. Van'T Hul, N. de Vries, B. Bloem (Nijmegen, Netherlands)

    Objective: Systematically review home-based physical capacity tests and their clinimetric properties in different patient populations with a chronic disease. Background: Physical capacity is a predictor…
  • 2023 International Congress

    Does hyposmia induce apathy in early Parkinson’s disease? Lessons from structural brain connectivity

    A. Martinez-Nunez, H. Soltanian-Zadeh, K. Latack, N. Ghazi, A. Mahajan (Detroit, USA)

    Objective: To study changes in microstructural integrity of white matter tracts associated with apathy in patients with early Parkinson’s disease (PD) and hyposmia Background: Smells…
  • 2023 International Congress

    24(S)-Hydroxycholesterol and cognition in Huntington’s disease: results from two large patient cohorts (TRACK-HD and ENROLL-HD)

    S. Gray, M. Lewis, T. Kazdoba, A. Koenig, E. Lefler, K. Paumier, M. Quirk, J. Doherty (Cambridge, USA)

    Objective: To investigate correlations between plasma levels of 24(S)-Hydroxycholesterol (24[S]-HC) and cognitive performance in participants with Huntington’s disease (HD) using data from ENROLL-HD. Background: HD…
  • 2023 International Congress

    Impairment of SHH signaling in PD LRRK2 I1371V iPSC derived floor plate cells contribute to ontogenic origin of lower dopaminergic-neuron yield

    I. Datta, S. Jagtap, C. Potdar, K. Singh (Bengaluru, India)

    Objective: To estimate SHH responsiveness & signaling of Floor Plate Cells (FPCs) derived from LRRK2 I1371V PD patient-iPSCs along with its link with LRRK2 I1371V…
  • 2023 International Congress

    Nutritional traits in the prodromal phase on Parkinson’s disease in community-dwelling older adults in Japan

    T. Yamaguchi, R. Nozaki, K. Taguchi, Y. Suzuki, K. Takahashi, K. Takahashi, K. Iwaoka, Y. Sato, T. Terauchi, H. Akasaka, N. Ishizuka, T. Maeda (Iwate, Japan)

    Objective: The objects of this study is to clarify the relationship between nutritional traits and the prodromal phase of PD in the community-dwelling older adults.…
  • 2023 International Congress

    Effect of Recognition of Vertical Posture on Forward Bending Posture in Patients with Parkinson’s Disease: A Multicenter Observational Study

    M. Shiraishi, K. Mikami, H. Kamo, T. Kamo, T. Tsunemi, Y. Okuma, K. Fujimoto, Y. Yokota, S. Nogawa, T. Osada, M. Seki, H. Nagayama, T. Hatano, H. Nakajima, K. Suzuki, T. Yamamoto, Y. Yamano, N. Hattori, M. Ijima (Kawasaki, Japan)

    Objective: The mechanisms of postural abnormalities in Parkinson’s disease are diverse but often intractable, and there are no established measures to prevent early-stage progression. Background:…
  • 2023 International Congress

    Introduction of a Parkinson’s Disease Virtual Ward Round

    K. Ramsay (Sutton-in-Ashfield, United Kingdom)

    Objective: To introduce an electronic alert when people with Parkinson’s disease (PwP) are admitted to Sherwood Forest Hospitals NHS Trust (SFH). Background: PwP are more…
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