Relationship of health-related quality of life (HRQoL) patterns with clinical diagnosis in patients with spinocerebellar ataxia (SCA) – A latent class analysis
Objective: The aim was to identify patterns of the EQ-5D-3L in patients with SCA to describe the relationship between the patient’s diagnosis and clinical parameters.…Fecal tyrosine decarboxylase and motor response complications in Parkinson’s Disease
Objective: To investigate the clinical correlates of gut microbe-derived tyrosine decarboxylase (tdc) and motor dysfunction in Parkinson’s Disease (PD) patients. Background: Gut microbe-derived tdc was…The association between compliance and the effects of home-based touchscreen training in Parkinson’s disease
Objective: To explore whether training success is determined by compliance as well as by cognitive function, depression and levodopa equivalent dosage (LEDD). Background: Training compliance…Cerebrospinal fluid biomarkers for diagnosis of Parkinson’s disease: a systematic review and network meta-analysis
Objective: In this study, we intended to use network meta-analysis to compare the diagnostic performances of different CSF biomarkers in the diagnosis and differential diagnosis…Recruiting for Parkinson’s disease risk: Successful engagement tactics to screen for hyposmia in undiagnosed individuals
Objective: Describe recruitment tactics for engaging community in Parkinson’s disease remote risk screening Background: Early clinical markers of PD are critical to identifying biomarker signatures…Informing people with Parkinson’s disease of their gene variant status: PD GENEration, a North American observational and registry study
Objective: To describe genetic testing results of major genes for Parkinson’s disease (PD) in a North American cohort as part of PD GENEration Background: Although…Dopamine depletion of striatal subregions and motor dysfunction in prodromal and clinical Parkinson’s disease
Objective: This aim of this study was to investigate how dopamine depletion of different striatal subregions contributes to motor symptoms in patients with prodromal and…Design of a Phase 2 Study of Suvecaltamide in Moderate to Severe Parkinson’s Disease Tremor
Objective: Describe the design of a phase 2 study (NCT05642442) of a once-daily, extended-release formulation of suvecaltamide to treat moderate to severe Parkinson’s disease tremor…Publication rates and characteristics of clinical trials in deep brain and responsive neurostimulation
Objective: We examine DBS and RNS trials from 1997-2022, chart their characteristics, and examine rates and predictors of results reporting. Background: Prompt dissemination of clinical…Harmonizing genetic testing for early-onset Parkinson’s disease: results of the PARKNET multicentric study
Objective: To harmonize the interpretation of genetic testing in Parkinson's disease (PD) across the PARKNET network, as well as to provide a comprehensive assessment of…
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