The Short Duration Response and Long Duration Response to L-Dopa are Needed to Restore Vigor-Motivation Coupling in Parkinson Disease
Objective: To assess the relationship between the Short Duration Response (SDR) and Long Duration Response (LDR) to L-Dopa therapy in Parkinson disease (PD) and restoration…Neuromelanin related 7T MRI of the locus coeruleus differs between Parkinson’s disease and controls
Objective: To compare the signal intensity of the substantia nigra and locus coeruleus on Magnetization Transfer 7T MRI between PD patients and healthy controls (HC)…Proteomic profiles analysis of plasma exosomes and WBC reveals news insights of PD patients classified into H&Y clinical stage
Objective: To perform a comparative proteomic analysis of WBC and exosomes in samples from PD patients and to compare with healthy controls (HC) using a…Effects of a small molecule angiotensin IV analog on Huntington’s disease animal model
Objective: The present study was designed to test if N-hexanoic-Tyr-Ile-(6)-amino hexanoic amide (AngIV-6a), an angiotensin IV analog, could attenuate 3-nitropropionic acid-induced Huntington’s disease-like symptoms in…Characterizing advanced Parkinson’s disease: OBSERVE-PD observational study – results of the Belgian subgroup
Objective: The primary objective of the study was to evaluate the proportion of Parkinson’s Disease (PD) patients in Movement Disorder Centers with Advanced Parkinson’s Disease…Improving inpatient medication management in hospitalized Parkinson’s patients
Objective: Develop a process for Parkinson's patients to provide individualized medication management to reduce length of stay,, mortality, 30-day readmissions, and increase patient satisfaction. Background:…The mGlu2 positive allosteric modulator AZD8529 alleviates L-DOPA-induced dyskinesia and psychosis-like behaviours in the parkinsonian marmoset
Objective: To assess the effect of the metabotropic glutamate 2 (mGlu2) receptor positive allosteric modulator (PAM) AZD8529 on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia and psychosis-like behaviours (PLBs)…Delta(0.5-2Hz) Spectral Power reduction in the frontal region in NREM Sleep are Associated with dyskinesia in Parkinson’s Disease
Objective: Our study aimed to establish the objective physiological indicators assessed by polysomnography(PSG) that are associated with dyskinesia in PD patients.Our study aimed to establish…Disruption of Locus Coeruleus-Related Functional Networks in Parkinson’s Disease
Objective: We used resting-state functional MRI (rs-fMRI) to investigate the alterations of functional connectivity (FC) of LC-related resting-state networks (RSNs) and the associations between RSNs…Effect of dietary caffeine on brain dopamine transporter binding in Parkinson’s disease
Objective: To investigate the relationship between dietary caffeine intake and striatal dopamine function over the progression of Parkinson’s disease (PD). Background: The association between high…
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