Home-based titration with Duodenal infusion of Levodopa in People with Parkinson’s disease: an observational feasibility study
Objective: Primary objectives were to assess the feasibility and safety of LCIG home titration with use of telemedicine-assisted (TM) technology, and patient/caregivers satisfaction. Secondly, to…Network localization of limb ataxia
Objective: To identify the neural substrates of limb ataxia caused by stroke lesions. Background: Ataxia is a neurological sign defined by incoordination of voluntary movements.…Mesencephalic neuroglial cyst can produce clinical manifestations and a metabolic [18F] FDG PET pattern mimicking a Progressive Supranuclear Palsy Syndrome
Objective: To describe the clinical manifestations and structural and functional neuroimaging findings in a patient with a left mesencephalic neuroglial cyst, resembling a PSP. Background:…Motor function in Parkinson´s disease during 16h treatment with intravenously (DIZ101), subcutaneously (DIZ102), or intestinally (LCIG) infused levodopa
Objective: To compare the effect of intravenous (DIZ101) and subcutaneous (DIZ102) continuous 16h infusion of a continuously buffered acidic levodopa/carbidopa solution with levodopa/carbidopa intestinal gel…Circadian rhythm and adaptive deep brain stimulation in essential tremor
Objective: We aim to develop a closed-loop adaptive deep brain stimulation (aDBS) system that turns DBS off based on the real-time detection of sleep using…Repetitive trans-spinal magnetic stimulation and kinesiotherapy could reduce motor and gait symptoms in patients with neurodegenerative ataxia?
Objective: To investigate whether a 1-week treatment with repetitive trans-spinal magnetic stimulation (rTSMS) combined with kinesiotherapy could reduce motor and gait symptoms in patients with…Analysis of α-Synuclein Seed Amplification Assay in Carriers of GBA and LRRK2 Pathogenic Variants
Objective: To assess α-synuclein seed amplification assay (αS-SAA) in cerebrospinal fluid (CSF) from a cohort of PD patients and non-manifesting carriers (NMCs) of pathogenic GBA…Detection and classification of GBA variants PD-related: is there sex unbalance?
Objective: This study aims to classify GBA variants detected in the Genetic Movement Disorders Laboratory (GMDL) of the Neurological Institute “Carlo Besta” in Milan over…Testing the applicability of the dysarthria analyzer to detect levodopa effects on speech in a German cohort of people with Parkinson’s disease
Objective: To test the applicability of “the dysarthria analyzer” in a levodopa challenge test to determine short term effects of levodopa on acoustic speech parameters.…Clinical and radiological gender differences in Parkinson’s disease
Objective: To assess clinical and brain metabolic gender differences in a cohort of patients with PD Background: Many studies have elucidated gender-related clinical differences in…
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