Role of the Alpha-synuclein Seed Amplification Assay in Parkinson’s Disease Clinical Trials: A Case Report of Multiple System Atrophy Misdiagnosed as Parkinson’s Disease
Objective: Report a patient with Multiple System Atrophy (MSA) misdiagnosed as Parkinson’s disease (PD) and enrolled in a clinical trial for PD treatment with Mesenchymal…Lyme disease presenting as a rapidly progressive MSA-C look alike
Objective: We report two cases of encephalomyelitis due to Lyme disease with cerebellar ataxia and autonomic symptoms, which presented with a rapidly progressive MSA-like phenotype.…Clinical and neuroimaging factors associated with survival in Progressive Supranuclear Palsy
Objective: To assess clinical and neuroimaging factors associated with survival in a cohort of patients with a final clinical diagnosis of Progressive Supranuclear Palsy (PSP)…Metabolic Progressive Subtypes in Progressive Supranuclear Palsy
Objective: To investigate disease-specific spatiotemporal progression in Progressive supranuclear palsy (PSP) patients using 18F-fluorodeoxyglucose (FDG) PET and the Subtype and Stage Inference (SuStaIn) algorithm, to…Stiff Person Syndrome developing into Corticobasal Syndrome: a case report.
Objective: To describe a case of Stiff Person Syndrome which developed into Corticobasal Syndrome Background: Stiff Person Syndrome (SPS) is a rare autoimmune movement disorder…AI for Personalized Medication Management in Parkinson’s Disease
Objective: To assess medication usage over time in Parkinson’s Disease utilizing AI in EHR data. Background: Parkinson's disease (PD) is a complex neurodegenerative disorder characterized…Exploring Vestibulopathy in PD: Distinguishing PD from Age-related Presbyvestibulopathy via Dynamic Gait and Balance Assessment
Objective: To investigate the influence of age-associated vestibulopathy (presbyvestibulopathy, PVP) on dynamic gait and balance in Parkinson's disease (PD) patients and elderly controls. We hypothesized…Baseline and Longitudinal NSD-ISS Staging of the PPMI Cohort
Objective: To apply biological definition and Neuronal α-Synuclein Disease Integrated Staging System (NSD-ISS) to the PPMI baseline and longitudinal dataset. Background: The NSD-ISS Working Group…Changes in Postural Control of Patients with Normal Pressure Hydrocephalus After Lumbar Puncture
Objective: To evaluate the alterations in postural control among patients diagnosed with normal pressure hydrocephalus (NPH) following lumbar puncture Background: Posturography is an indispensable tool…Driving assessment in older patients with Parkinson’s in United Kingdom.
Objective: To review existing pathway for driving assessment in older Parkinson’s patients in Royal Berkshire Hospital, Reading, UK. Background: Parkinson’s leads to motor, cognitive and…
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