Correlation between specific lower limb muscle strength and postural instability and gait difficulties in Parkinson’s disease
Objective: To explore the relationship between the strength of specific lower limb musclegroups and their associations with PIGD motor features. Background: Postural instability and gait…The Freezing of Gait Change of Direction (FOG-COD) Test: A Novel Measure to Predict Falls
Objective: To examine the relationship between freezing of gait (FOG), falls history, and a novel clinical measure in persons with parkinsonism. Background: Freezing of gait…Development and Feasibility Trial of iSupport-PD, a Digital intervention for carers of people with Parkinson’s and Cognitive Impairment
Objective: Develop a digital intervention to prevent or decrease the mental and physical health problems associated with caring and improve quality of life of carers…Predictors of Death within 6 Months in Individuals with Dementia with Lewy Bodies
Objective: To assess predictors of death in the subsequent 6 months in dementia with Lewy bodies (DLB). Background: Individuals with DLB commonly die of disease-related…Unmet Motor and Nonmotor Needs of People with Parkinson’s in the Final Year of Life
Objective: To assess main issues People with Parkinson’s (PD, PwP) wished to discuss at clinical consultations with movement disorders specialists during the final year of…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS). A Phase II clinical trial – ISRCTN99462035.
Objective: The NORAPS Phase II clinical trial seeks to demonstrate safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a…Personality may influence the response to apomorphine infusion in Parkinson’s disease patients
Objective: to evaluate the impact of personality on quality-of-life (QoL) amelioration after treatment by Continuous Subcutaneous Apomorphine Infusion (CSAI) in Parkinson’s disease (PD). Background: PD…A Phase 2 Randomized Clinical Trial of TAK-071, an Acetylcholine M1 Receptor Positive Allosteric Modulator, in Parkinson Disease with Cognitive Impairment
Objective: To study the safety and efficacy of TAK-071, an M1 positive allosteric modulator, in adults with Parkinson disease (PD) with increased risk for falls…Impact of IPX203 on Parkinson’s patients’ motor states upon awakening: analysis of patient diary data
Objective: To evaluate “On” upon awakening in Parkinson’s disease patients taking IPX203 in the RISE-PD phase 3 clinical trial. Background: IPX203 is a novel extended-release,…The HIIT-Home4Parkinson’s study
Objective: This study aims to evaluate the practicality and utility of a novel, co-created home-based high-intensity interval training (HIIT) programme for people with Parkinson’s (PwP).…
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