Proposed framework to evaluate the ability of digital measures to track early stage Parkinson’s disease progression
Objective: To introduce a technical framework for evaluating digital measures for their ability to track Parkinson’s disease (PD) progression and apply the framework to digital…Territorial inventory of training needs in nursing home for the support of patients with Parkinson’s syndrome
Objective: - Raise awareness among the various professionals in contact with patients suffering from Parkinson's syndromes- Optimize follow-up and support- Avoid emergency room visits through…Clinico-radiological Spectrum and Predictors of Disease Severity in Neurological Wilson Disease: A Single Center Observational Study.
Objective: To determine the Clinical and radiological spectrum of neurological Wilson’s disease (WD) and predictors of disease severity. Background: Wilson’s Disease (WD) is autosomal recessive,…Anosognosia for hardware-related complications in deep brain stimulation
Objective: In this series, we report two rare cases of selective unawareness to hardware-related complications in deep brain stimulation (DBS). Background: DBS has shown good…Neurophenomenological Aspects of Monocular Visual Hallucinations in Charles Bonnet Syndrome in a patient with Parkinson’s Disease
Objective: This inquiry aims to augment understanding of Charles Bonnet Syndrome (CBS) by scrutinizing both monocular and bilateral visual hallucinations. It focuses on an atypical…Serotonin Transporter Dynamics in Multiple System Atrophy: Insights from 123I-FP-CIT SPECT Imaging
Objective: We aimed to visualize a serotonin transporter (SERT) based on 123I-FP-CIT SPECT, and assessing the binding distribution characteristics of the brainstems between patients with…Explore cellular heterogeneities of orbitofrontal cortex in multiple system atrophy using spatial transcriptomics
Objective: To explore the spatial organization and cellular complexity of the orbitofrontal cortex (OFC) in multiple system atrophy (MSA) via spatial transcriptomic (SRT). Background: The…Legmain/Asparaginyl endopeptidase-resistant tau fibril fold produces corticobasal degeneration-specific C-terminal tau fragment
Objective: This study monitored the formation of CBD (corticobasal degeneration)-type fibrils that exhibit astrocytic plaques, a characteristic CBD pathology, using Legumain-cleavage site-specific antibodies and CBD-specific…Combined application of alpha-synuclein and 4-repeat tau seed amplification assays for the differential diagnosis of parkinsonian disorders
Objective: To assess alpha-synuclein (a-syn) and 4-repeat tau (4RT) seed amplification assay (SAA) positivity rates in biosamples from people with Parkinson’s disease (PD) and Progressive…Hydrocephalic Progressive Supranuclear Palsy: An Underrecognized Entity
Objective: We describe a case of NPH-like presentation of PSP, review literature surrounding this entity, and discuss key diagnostic considerations and implications. Background: Despite advances…
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