Development of a Beta-sensing Pathway in Deep brain stimulation to optimise utility of Local field potential recordings using the Percept system. (Newcastle Beta-sensing Algorithm – NBA)
Objective: To establish a pathway for utilisation of beta-sensing using the Percept technology which is applicable to real world clinical practice and optimises the utility…Efficiency of AI-Based Service for Screening Diagnostics of Parkinson’s Disease (Brainphone Project)
Objective: The aim of the clinical study was the assessment of efficiency of the screening diagnositics method for Parkinson's disease (PD) by voice using AI-based…A Scoping Review of Epidural Spinal Cord Stimulation in the Treatment of Multiple Movement Disorder Symptoms
Objective: Conduct a scoping review to examine the effects of epidural spinal cord stimulation on multiple clinical symptoms of movement disorders. Background: Prior research has…SMaRT-PD: A Clinical Decision Support System for the Management of Parkinson’s Disease
Objective: To optimise the accuracy of a clinical decision support system (CDSS) to support Self-Management, Remote monitoring and Timely review in Parkinson’s Disease (SMaRT-PD). Background:…Empower-PD: “An Exploratory Investigation of Accelerometer Data on Parkinson’s Patients’ Motor Symptoms and the Correlation with Quality of Life.”
Objective: To describe weekly changes in bradykinesia-score (BKS) measured on objective wearable data and assess the correlation between these changes and Quality of Life (QoL)…How does the PPP2R2B mutation alter neuronal cytoskeletal structure in SCA12
Objective: To study the effect of the PPP2R2B mutation on human induced pluripotent stem cell (iPSC) derived neurons in SCA12 patients. Background: SCA12 is an…Pulmonary Dysfunction in Friedreich’s Ataxia (FRDA)
Objective: We sought to characterize pulmonary function in FRDA and identify disease variables that may contribute to dysfunction. Background: FRDA is a neurodegenerative disease that causes…Substantia Nigra Degeneration In Spinocerebellar Ataxia 2 And 7 Using Neuromelanin-Sensitive Imaging
Objective: To assess substantia nigra pars compacta (SN) degeneration in SCA type 2 and 7 using neuromelanin-sensitive MRI Background: Spinocerebellar ataxias (SCA) are often associated…Clinico-radiological and genetic profile of patients with Ataxia with Oculomotor apraxia type-2 (AOA2)- A case series from India
Objective: To delineate clinical, radiological and genetic profile of patients with ataxia with oculomotor apraxia type-2 (AOA2) in Indian cohort. Background: AOA2 is a relatively…A study on the phenomenological analysis of Spinocerebellar Ataxia type 12 revealing a dystonic imprint
Objective: To assess the presence and distribution of dystonia in spinocerebellar ataxia type 12 (SCA12). Background: SCA12, commonly seen in the Agarwal community in India,…
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