MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2024 International Congress

    Deep Brain Stimulation of the Subthalamic Nuclei in Advanced Parkinson’s Disease what Effects on Motor Non-motor and Neuropsychological Functions a Monocentric Prospective Study with a 12-month Follow-up

    V. Leclercq, B. Delsaut, V. Donckels, S. Dethy (Sint-Pieters-Leeuw, Belgium)

    Objective: The aim of the study is to assess the evolution of motor symptoms (MS), non-motor symptoms (NMS) and neuropsychological functions (NF) in Parkinson's disease…
  • 2024 International Congress

    Case Report Increasing ‘On-time’ Using Mucuna pruriens Concomitantly with Traditional Levodopa/carbidopa Management

    T. Denne (United States, USA)

    Objective: Case study to see if concomitant use of the botanical Mucuna pruriens with traditional levodopa/carbidopa management could improve patient ‘off-time.’ Background: Mucuna pruriens is a pantropical legume…
  • 2024 International Congress

    ilex Paraguariensis (Yerba mate) modulates the AMPK pathway and downstream key metabolic mechanism that may explain its neuroprotective role.

    J. Ferrario, H. Hauche, L. Tschopp, T. Eidelman, M. Bordone (Buenos Aires, Argentina)

    Objective: To investigate the molecular pathways regulated by yerba mate [YM] extract and its main active compounds in a neuronal cell line as a cue…
  • 2024 International Congress

    Simulated Space Gravity Recapitulates Parkinson’s Disease Pathology in Neural Cell Model

    V. Lentini, G. Uras, A. Manca, M. El Faqir, S. Lucas, A. Schapira, A. Pantaleo (Sassari, Italy)

    Objective: This investigation centers on the potential influence of microgravity on α-synuclein aggregation, a hallmark feature of Parkinson's disease (PD) characterized by the formation of…
  • 2024 International Congress

    Identification of Pre-Diagnostic Biomarkers for Parkinson’s Disease from Plasma Proteome

    M. Ta, E. Appleton, S. Khosousi, A. Sturchio, I. Markaki, W. Paslawski, C. Blauwendraat, M. Nalls, A. Singleton, P. Svenningsson, H. Iwaki (Bethesda, USA)

    Objective: To identify pre-diagnostic biomarkers for Parkinson’s Disease (PD) from the plasma proteome. Background: The plasma proteome is a non-invasive and accessible measure to assess…
  • 2024 International Congress

    Safety and Tolerability of Bemdaneprocel in People With Parkinson’s Disease: Results up to 24 Months From a Phase 1 Study

    H. Sarva, C. Henchcliffe, A. Lozano, A. Fasano, S. Kalia, K. Yu, C. Brennan, W. Stemple, N. Abid, M. Yountz, A. Enayetallah, A. Lampron, V. Tabar (New York, USA)

    Objective: To report the safety and tolerability of bemdaneprocel in participants with Parkinson’s disease (PD) up to 24 months post transplantation. Background: Bemdaneprocel is an…
  • 2024 International Congress

    Neuroimaging Factors Differentially Associated with Pathology and Clinical Presentation

    J. Pommy, S. Bouchachi, A. Bryant, V. Thornton, C. Nguyen, J. Truelove, K. Rawson, J. Icehour, M. Knopp, C. Wright, D. Scharre (Columbus, USA)

    Objective: Examine utility of a factor analysis approach to neuroimaging data in Lewy body disease (LBD) and Alzheimer’s disease (AD). Background: Significant heterogeneity exists among patients…
  • 2024 International Congress

    Mitochondrial Complex I Brain Imaging in Parkinson’s Disease and Lewy Body Dementia

    S. Berman, J. Stehouwer, C. Mathis, W. Klunk, H. Tsukada, S. Royse, A. Reese, T. Overbey, J. Greenamyre, G. Sjobeck, D. Tudorascu, B. Lopresti (Pittsburgh, USA)

    Objective: To compare brain mitochondrial respiratory Complex-1 (mito-C1) between Parkinson’s disease (PD) and PD dementia/Dementia with Lewy Bodies (PDD/DLB) participants and unimpaired controls, using 18F-BCPP-EF,…
  • 2024 International Congress

    First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease

    C. Laurencin, S. Lancelot, S. Brosse, J. Redouté, I. Mérida, D. Le Bars, N. Costes, S. Thobois, P. Boulinguez, B. Ballanger (lyon, France)

    Objective: To investigate the relationship between in vivo noradrenergic markers and olfactory impairment in patients with Parkinson’s disease (PD). Background: Degeneration of the noradrenergic (NA)…
  • 2024 International Congress

    Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD

    H. Hameed, S. Elasfar, K. Ehgoetz Martens (Waterloo, Canada)

    Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…
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