Mapping the Efficacy Landscape: A Network Meta-Analysis of Pharmacological Interventions in Huntington’s Disease
Objective: To evaluate and compare the efficacy of pharmacological interventions for Huntington's Disease through a network meta-analysis, identifying the most effective treatments. Background: Huntington’s Disease…Pitolisant as adjunct therapy for refractory restless legs syndrome
Objective: Determine the efficacy and tolerability of pitolisant for adjunct therapy in patients with refractory restless legs syndrome (RLS) Background: RLS treatments include iron, dopaminergics,…A Review of the Genetic Spectrum of Hereditary Spastic Paraplegias in the Middle East and North Africa Region
Objective: To systematically review existing literature and collect data on Hereditary Spastic Paraplegias(HSP) in the Middle East and North Africa(MENA), aiming to assess the prevalence…How Common is Essential Tremor in Germany? A Real-World Claims Data Analysis
Objective: To estimate the prevalence and incidence of essential tremor (ET) stratified by age and sex, using insurance claims data from a large representative [1,2]…A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of OnabotulinumtoxinA for the Treatment of Upper Limb Essential Tremor: ELATE Trial
Objective: Here, we present the eligibility criteria and study design of ELATE, a Phase 2b clinical trial evaluating the safety and efficacy of onabotA compared…Genetic Analysis of UK Kindreds with Familial Tremor in The Global Parkinson’s Genetics Progam (GP2)
Objective: To gain a better understanding of the genetic basis of familial tremor syndromes. Background: The genetic basis of tremor is poorly understood and familial…Movement Disorders In Children With Monoamine Neurotransmitter Disorders
Objective: To describe clinical, para-clinical, therapeutic and evolutionary characteristics of movement disorders (MD) and oculogyric crises (OC) in children with monoamine neurotransmitter disorders (MND) Background:…Parkinsonism in combined Fragile X and XYY Syndromes: A Case Report
Objective: We describe an unusual case of parkinsonism in a 45-year-old male with Fragile X syndrome and XYY syndrome. Background: Fragile X syndrome (FXS) is…A Benign Course of Parkinson’s Disease Associated with Different Mutations in the Glucocerebrosidase (GBA) Gene – a Case Series.
Objective: To describe a subtype of GBA-associated Parkinson's disease with a benign motor and cognitive course of disease. Background: Subjects carrying mutations in the GBA…Remote DNA Collection for Parkinson’s Research: Insights from AccessPD
Objective: Established in 2022, the AccessPD registry aims to create a comprehensive database of electronic health records, self-reported outcomes, and genetic data from Parkinson's disease…
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