Pathways for diagnosis and multimodal management, including botulinum neurotoxin therapy, in shoulder conditions following central lesions
Objective: To build on existing publications and give guidance for healthcare providers managing shoulder conditions following central lesions, including how to identify, diagnose, and treat…Suvecaltamide Metabolites Are CaV3 Modulators and Contribute to Pharmacological Effect
Objective: To determine the potency-concentration relationships and combined pharmacological effects for suvecaltamide and its 2 active metabolites (JZZ05000034=M01, JZZ05000035=M02; total active moiety [TAM]). Background: T-type…Cortical response to proprioceptive stimulation in orthostatic tremor – a magnetoencephalography study
Objective: To investigate cortical integration of proprioceptive information in patients with orthostatic tremor (OT), measured as event-related synchronisation (ERS) response to proprioceptive stimulation using magnetencephalography…Secondary orthostatic tremor associated with hyperthyroidism: A case report
Objective: To illustrate the electrophysiological and clinical findings in a patient with secondary orthostatic tremor (OT) associated with hyperthyroidism Background: Orthostatic tremor is a rare…Movement Disorders Associated with Infectious Encephalitis in Pediatric Patients
Objective: The objective of our study is to report the clinical and imaging profile of a cohort of pediatric patients with movement disorders (MDs) associated…Expanding the phenotypic spectrum of movement disorders in 22q11.2 deletion syndrome
Objective: To formally characterize the evolving spectrum of movement disorders associated with chromosome 22q11.2 deletion syndrome Background: Emerging evidence suggests that a wide range of…The functional consequences of the ‘African GBA1 allele’ of rs3115534 in Parkinson’s Disease
Objective: To gain insights into the pathophysiology by which the G-allele of rs3115534 confers risk for PD. Background: A recent paper defined the G-allele of…RAB32 c.213C>G (p.Ser71Arg) explains Parkinson’s disease in two UK families: description of the clinical and biochemical features
Objective: To describe the clinical features, family structure of two families identified to have the recently described pathogenic variant RAB32 c.213C>G (p.Ser71Arg). Background: Genetic mutations…Utilizing a global network to study environmental factors relating to Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)
Objective: To identify and collect data on non-genetic variables from individuals with and without Parkinson’s disease (PD) in the Global Parkinson’s Genetics Program (GP2, http://gp2.org/).…Parkinson’s Disease Risk Genotypes at the GPNMB Locus Associate with Extent of Post-mortem Lewy Pathology
Objective: To determine whether Parkinson’s disease (PD) risk genotypes at the GPNMB locus associate with distribution of Lewy pathology in brain samples from a spectrum…
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