Metabolomic breath landscape analysis unravels lipid biomarker candidates in patients with monogenic and idiopathic Parkinson’s disease
Objective: We propose an untargeted metabolomics approach using exhaled breath analysis to (1) characterize the non-volatile metabolomic breath signature of Parkinson’s disease (PD) patients with…Quantitative Digitography and Home Diaries for PD Motor State Evaluation
Objective: Assess the feasibility of people with Parkinson’s (PwP) performing 30 seconds of repetitive alternating finger presses using Quantitative Digitography (QDG) technology every 30 minutes…CSF Mitochondrial DNA Indicates Body Composition and Energy Metabolism in Parkinson’s Disease.
Objective: This study aimed to elucidate the associations between cerebrospinal fluid (CSF) cell-free mitochondrial DNA (cf-mtDNA) levels and body composition, nutritional status, and metabolic biomarkers…Characterization of DBS-induced Speech Improvements in a German PD Cohort
Objective: To investigate speech changes induced by subthalamic deep brain stimulation (DBS) in persons with Parkinson’s disease (pwPD). Background: Dysarthria is a common debilitating motor…Digital measurement of ocular microtremor in Parkinson’s Disease: Analytical and clinical validation
Objective: This pilot study examined the analytical and clinical validation of OMT measurement via the iTremor ONE device in PwPD. Background: Ocular microtremor (OMT) is…Personality Traits and Neuropsychiatric Assessment in De Novo, Clinically Established Body-First and Brain-First Parkinson’s Disease
Objective: To assess and compare personality profiles and psychiatric symptoms in de-novo clinically-established body-first and brain-first PD. Background: Body-first and brain-first have recently been proposed…Exploring Uncertainties and Fears of People with Parkinson Disease
Objective: To assess the burden of uncertainties, hopes, and fears of people with Parkinson disease (PwP). Background: Parkinson disease (PD) is associated with significant psychosocial…Neurophysiological research on inhibitory processes in Parkinson’s disease
Objective: To explore neural mechanisms of inhibitory control, specifically differentiating reactive from prepared inhibitory processes, by synthesizing recent intracranial EEG (iEEG) studies and neurophysiological research…Episodic Simulation in Parkinson’s Disease (PD)
Objective: Characterize episodic simulation capabilities in non-depressed, non-amnestic patients with PD compared to healthy controls using autobiographical interviewing techniques. Background: Cognitive decline in PD occurs…Orthostatic Hypotension and Acute Cognitive Dysfunction in Parkinson’s Disease: Insights from fNIRS
Objective: To define cerebral oxygenation changes during positional cognitive testing in Parkinson’s disease (PD), comparing those with orthostatic hypotension (OH+) to those without (OH-). Background:…
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