Biological Predictors of Clinical Domains in Isolated REM Sleep Behavior Disorder with and without Synucleinopathy and Dopamine Dysfunction
Objective: To determine if baseline biomarkers predict baseline and progression of clinical domains in isolated REM sleep behavior disorder (iRBD). Background: iRBD has high conversion…Differentiation of Parkinsonian Syndromes Using Cognitive Strategies and Associations with Non-tremor Motor Progression
Objective: This study aims to investigate whether cognitive strategies on verbal fluency tasks differentiate Parkinson’s disease (PD) from Progressive Supranuclear Palsy (PSP) and healthy adults, and are associated with the progression of clinical motor symptoms in Parkinson’s…Smartphone Video Derived Digital Motor Phenotypes of MDS UPDRS-Related Tasks via a Comprehensive Motor Function Test
Objective: To develop an easy-to use Comprehensive Motor Function Test (CMFT) that combines active MDS‑UPDRS motor tasks with continuous body landmark tracking in smartphone videos…Voxel-Based Morphometry Reveals Gray Matter Volume Reductions in Sporadic Dystonia
Objective: To investigate gray matter (GM) volume changes in sporadic dystonia (SD) using T1 MRI and voxel-based morphometry (VBM). Background: Dystonia is a hyperkinetic movement…Retrospective Evaluation of microRNA-7-5p and Neuron-Derived α-Synuclein in Prodromal Parkinson’s Disease as Phenoconversion Biomarkers
Objective: To determine if combining microRNA-7-5p (miR-7-5p) and neuron-derived extracellular vesicle (NDEV) α-synuclein (α-syn) would enrich prodromal Parkinson's disease (PD) subjects for those more likely to phenoconvert. Background: Studies have found blood…Device-Assisted Therapies in Parkinson Disease: Patient Preference Following Nurse-Led Education
Objective: The study aims to evaluate treatment preferences and factors influencing decisions following structured Parkinson Disease Nurse Specialist (PDNS)-led Device Assisted Therapy (DAT) education. Background:…Altered local synchronization and functional connectivity in Patients with Parkinson’s Disease
Objective: This study aimed to identify the alterations of local synchronization and functional connectivity in PD and explore the acute neural response to acupuncture stimulation…Clinical and Mobility Outcome with Ring versus Directional Globus Pallidus Stimulation in Parkinson’s Disease
Objective: To compare therapeutic directional versus ring stimulation effects on clinical and objective mobility outcomes and beta band in people with Parkinson’s disease (PD) undergoing…Plasma Exchange and Reduced Parkinson’s Disease Diagnosis: A Nationwide Sequence Symmetry Analysis
Objective: To investigate temporal associations between plasma exchange, dialysis exposure, and PD diagnosis using a nationwide administrative database in Japan. Background: Emerging evidence suggests that…Opsoclonus-Myoclonus-Ataxia Syndrome in Adults: Case Series in Vietnam
Objective: To describe the clinical features, diagnostic findings, and treatment outcomes of adult OMAS cases in Vietnam. Background: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neurological…
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