Variants in Cytochrome P450–encoding Genes Associated with Parkinson’s Disease
Objective: To characterize the clinical features of PD associated with CYP gene variants (CYP‑iPD) and parkinsonism observed in other neurodegenerative diseases. Background: Cytochrome P450 (CYP)…Prognostic Factors for Survival in Multiple System Atrophy: A Retrospective Cohort Study with Focus on Surgical Interventions
Objective: To investigate prognostic factors associated with survival in patients with multiple system atrophy (MSA), with particular focus on surgical interventions. Background: MSA is a…Effects of Repetitive Deep TMS on Motor Function and Cerebral Perfusion in Parkinson’s Disease
Objective: This study aimed to investigate the effects of deep repetitive transcranial magnetic stimulation (dTMS) using an H-coil on cerebral perfusion and motor function in…Progressive Spastic Ataxia Associated with a GRM1 Variant in a Young Female
Objective: To report a young patient with progressive spastic ataxia and optic atrophy harboring a GRM1 variant. Background: Spinocerebellar ataxia type 44 (SCA44) is a…Single-Cell Transcriptomics and Experimental Models Implicate Functional Hypoxia in Microglial DAM Polarization and α-Synuclein Accumulation, with Involvement of HIF-1α, in Parkinson’s Disease
Objective: To investigate whether microcirculatory impairment-induced hypoxia contributes to the emergence of a late-stage disease-associated microglia (DAM) phenotype and impaired α-synuclein clearance in Parkinson's disease…Dopaminergic reconfiguration of an inverted network hierarchy in Parkinson’s disease
Objective: To determine how acute dopaminergic treatment reshapes large-scale brain network organization in Parkinson’s disease (PD). Background: Dopamine replacement reliably improves motor symptoms in PD,…Synchronous Unilateral Pendular Nystagmus and Palatal Myoclonus After Pontine Hemorrhage: A Case Report
Objective: To present a post-stroke pontine bleed patient who developed a rare movement disorder with a treatment approach. Background: A 43-year-old male presented with involuntary…Relationship Between Perceived and Actual Gluteal Muscle Activation in Parkinson’s Disease
Objective: To examine the relationship between the subjective sense of gluteal activation and actual muscle activity during a quadruped hip extension task in individuals with…Investigating the role of ATP7B heterozygous variants in Parkinson’s Disease
Objective: WD often includes parkinsonism and copper dysregulation is implicated in Parkinson’s disease (PD), we investigated whether heterozygous ATP7B variants are associated with increased PD…Seven-Year Outcome of Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson’s Disease Patients
Objective: To assess 7-year outcomes of unilateral MRI-guided focused ultrasound (MRgFUS) ventral intermediate nucleus thalamotomy in tremor-dominant Parkinson’s disease (TDPD) patients with levodopa-unresponsive tremor, and…
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