A Novel Bedside Clinical Test (“Vibration” Sign) Improves Diagnostic Differentiation of Functional Movement Disorders: A Prospective Pilot Study
Objective: To assess the diagnostic accuracy, inter-rater reliability, and clinical feasibility of the “vibration” sign for identifying Functional Movement Disorders (FMD). Background: FMD account for…Heterogeneous Responsiveness to Combined Motor–Cognitive Exercise in Parkinson’s Disease: A Latent Class Analysis
Objective: To evaluate the effects of a combined motor–cognitive exercise intervention in individuals with Parkinson’s disease (PD) and to explore latent response subgroups to identify…Hip and Elbow Joint Angle Characteristics of Patients with Parkinson’s Disease
Objective: This study aimed to examine the hip and elbow joint angles during walking in Parkinson’s disease patients compared to healthy individuals. Background: Parkinson’s disease…Pulsatile Striatal Dopamine Dynamics Drive Levodopa Induced Dyskinesia In Advanced Parkinson Disease
Objective: To determine how pathological striatal dopamine fluctuations relate to dyskinesia and motor output in levodopa induced dyskinesia. Background: Levodopa induced dyskinesia is a major…Differential Effect of MAO-B Inhibitors in GBA1 Carriers with Parkinson’s Disease Women vs Men
Objective: To investigate the longitudinal impact of MAOIs on motor progression among Parkinson's disease (PD) patients carrying GBA1 mutations, with an emphasis on sex-stratified clinical…Determinants of depression severity in patients of Spinocerebellar ataxia 12
Objective: To evaluate clinical and radiological co-relates of depression in Spinocerebellar ataxia -12 Background: Spinocerebellar ataxia type 12 (SCA12), caused by a CAG repeat expansion…Outcomes from Unilateral MR-Guided Focused Ultrasound Pallidothalamic Tractotomy for Advanced Parkinson’s Disease
Objective: To evaluate the safety, efficacy, and patient-reported outcomes of unilateral MRgFUS pallidothalamic tractotomy (PTT) for the treatment of aPD. Background: In July 2025, the…Diagnostic Delay in Multiple System Atrophy: Sociodemographic and Clinical Predictors in a Single-Center Cohort
Objective: To evaluate sociodemographic and clinical predictors of diagnostic delay in multiple system atrophy (MSA) at a single tertiary referral center. Background: MSA is a…The Effects of War on Patients with Parkinson’s Disease
Objective: In this study, we aim to evaluate whether patients perceived stress more than healthy controls and what symptoms were correlated with this stress by…Genetic determinants of cognitive performance in Parkinson’s disease: impact of distal regulatory variation at the SNCA locus in the gp2 cohort
Objective: This study evaluates the association between a distal regulatory haplotype at the SNCA locus and cognitive performance, measured by the Montreal Cognitive Assessment (MoCA),…
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