Beyond Relaxation: Can Self-Initiated Therapeutic Tremors Improve Functional Gait and ADL in Parkinson’s Disease?
Objective: The primary aim of this study was to investigate the effects of exercise with and without self-initiated unclassified therapeutic tremors (SUTT) on dynamic balance…Olfactory Groove Meningioma Presenting with Recurrent Falls and Dystonic Head Tremor An Unusual Clinical Presentation
Objective: To describe a rare presentation of olfactory groove meningioma. Background: Olfactory groove meningioma is a benign intracranial tumor arising from the dura of the…Targeted Repeat-Expansion Screening Highlights Unmet Genomic Needs in Genetically Naive Ataxia: A Ukrainian Single-Centre Pilot Study
Objective: To assess the diagnostic yield of targeted repeat-expansion testing in patients with genetically naïve ataxia after exclusion of secondary causes. Background: Progressive ataxia is…Azathioprine-associated changes in peripheral–central immune signalling in Parkinson’s disease: post-hoc analysis of AZA-PD
Objective: To assess whether changes in peripheral markers of CNS immune cell trafficking relate to clinical response to azathioprine in AZA-PD Background: We conducted a…An Optimized Workflow for High-Throughput RNA-Seq from Human Deep Brain Tissue Using DBS Microelectrodes
Objective: To optimize a workflow for extracting human deep brain RNA from DBS microelectrodes for transcriptome sequencing. Background: Understanding the molecular mechanisms of Parkinson’s disease…Reduced Motor Unit Discharge Variability of Wrist Muscles 24 Hours After Closed-Loop Electrical Stimulation in Essential Tremor
Objective: To investigate the acute and sustained effects of two peripheral electrical stimulation strategies on motor unit activity of wrist flexors and extensors in individuals…REM Sleep Behavior Disorder and Clinical Progression in Multiple System Atrophy
Objective: To investigate clinical characteristics of REM sleep behavior disorder (RBD) in multiple system atrophy (MSA) and evaluate associations with disease severity, autonomic dysfunction, and…Kinematic Characterization of Upper Limb Tremor Distribution in Essential Tremor
Objective: To quantitatively characterize the anatomical distribution of tremor power in patients with essential tremor (ET) and determine which joint-specific contributions most strongly correlate with…Phenotypic Overlap Between Essential Tremor and Dystonic Tremor: Diagnostic Features, Misclassification, and Clinical Implications :A Systematic Review
Objective: To review evidence identifying clinical and neurophysiologic features that distinguish essential tremor from dystonic tremor and highlight patterns associated with diagnostic misclassification. Background: Distinguishing…Digital Biomarkers of Spinocerebellar Ataxia Type 3: Wearable Sensor Metrics during Turning and Postural Adjustments
Objective: To evaluate whether movement parameters derived from wearable inertial sensors differentiate individuals with SCA3 from healthy controls and whether these parameters correlate with clinical…
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