Effects of Manual Therapy on Hand Dexterity in Children Aged 4–8 Years: A Prospective Interventional Study
Objective: This study aimed to evaluate the effect of a structured manual therapy program on hand dexterity in young children. Background: Impaired hand dexterity is…Active Contact Localization in the Subthalamic Nucleus Predicts Phonemic Fluency Decline After Bilateral STN-DBS
Objective: To test whether active contact location within the subthalamic nucleus (STN) predicts postoperative change in phonemic fluency (PF) after bilateral STN deep brain stimulation…Risk of Deep Venous Thrombosis in Patients With Parkinson’s Disease: A Meta‑Analysis of Observational Studies
Objective: To compare the risk of deep venous thrombosis (DVT) in patients with Parkinson’s disease (PD) versus non‑PD. Background: Patients with PD may have an…Accessible Assessment of Ataxia Severity Across Diverse Populations: Integrating Large Datasets, Machine-Learning, and Online Testing
Objective: To explore whether internet-based assessments combined with machine learning approaches can support scalable characterization of ataxia severity. Background: In-person assessments of ataxia severity are…Feasibility of the ActivPARK Study – Longitudinal Assessment of Physical Activity in People with Parkinson’s Disease
Objective: To evaluate the feasibility designed to inform a future national cohort study assessing physical activity (PA) and health longitudinally in people with Parkinson’s disease…The Impact of Demographic Factors on Skull Density Ratios in a Hawaii Cohort
Objective: To understand the impact of demographic factors on skull density ratio (SDR) in Hawai‘i patients. Background: SDR is a validated indicator of the ability…Association Between Sleep Disturbance and Fatigue in Patients with Parkinson’s Disease
Objective: This study aimed to comprehensively investigate the associations between sleep disturbance and several non-motor symptoms, with a particular focus on the relationship with fatigue.…Opicapone as adjunct to levodopa in Chinese patients with Parkinson’s disease and wearing-off: a randomized, double-blind, placebo-controlled phase 3 trial
Objective: To evaluate the efficacy and safety of once-daily opicapone as adjunct to levodopa in Chinese patients with Parkinson’s disease (PD) and wearing-off, and to…DDX17 Drives Astrocytic Mitochondrial Metabolic Reprogramming and Contributes to Parkinson’s Disease Progression
Objective: To investigate whether DDX17, an RNA helicase identified as a Parkinson's disease (PD) risk gene, regulates astrocytic mitochondrial metabolism and contributes to dopaminergic neuron…REM Sleep Behaviour Disorder (RBD) and its relation to Non-motor Symptoms in Progressive Supranuclear Palsy(PSP).
Objective: To examine the frequency of RBD in PSP and its associations with other non-motor symptoms. Background: RBD once considered rare in PSP, is now…
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